PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING METABOLIC DISEASE COMPRISING DEMETHYLZEYLASTERAL

A composition containing demethylzeylasteral or a pharmaceutically acceptable salt thereof of the present invention is a glucocorticoid receptor antagonist, which has excellent effects of inhibiting intracellular glucocorticoid receptor activity and inhibiting the accumulation of fat cells for the p...

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Bibliographische Detailangaben
Hauptverfasser:	KIMRA, YOON JUNG HAN, SHIN SEO HYUN, LEE KI WON, HUR GI HYUN, LEE JOON YOUNG, YANG HEE, KIM YE EUN
Format:	Patent
Sprache:	eng ; kor
Schlagworte:	FODDER FOODS OR FOODSTUFFS FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
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Beschreibung
Zusammenfassung:	A composition containing demethylzeylasteral or a pharmaceutically acceptable salt thereof of the present invention is a glucocorticoid receptor antagonist, which has excellent effects of inhibiting intracellular glucocorticoid receptor activity and inhibiting the accumulation of fat cells for the prevention and treatment of metabolic diseases. 본 발명의 디에틸제일아스테럴 또는 이의 약학적으로 허용되는 염을 포함하는 조성물은 글루코코르티코이드 수용체의 길항제로서 세포 내 글루코코르티코이드 수용체 활성을 억제하고 대사성 질환의 예방 및 치료를 위한 지방 세포의 축적 억제에 우수한 효과를 가진다.