1R2S-1-6--2--3--4--2-1--1---2- PROCESS FOR PREPARING 1R2S-1-6-bromo-2-methoxyquinolin-3-yl-4-dimethylamino-2-1-naphthyl-1-phenyl-butan-2-ol AND PHARMACEUTICALLY ACCEPTABLE SALT
The present invention relates to a method for manufacturing (1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-4-dimethylamino-2-(1-naphthyl)-1-phenyl-butan-2-ol comprising a method for separating (1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-4-dimethylamino-2-(1-naphthyl)-1-phenyl-butan-2-ol capable of mass p...
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| creator | KIM JAEHAN KIM YONG JIK SHIN CHANG YONG |
| description | The present invention relates to a method for manufacturing (1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-4-dimethylamino-2-(1-naphthyl)-1-phenyl-butan-2-ol comprising a method for separating (1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-4-dimethylamino-2-(1-naphthyl)-1-phenyl-butan-2-ol capable of mass production with an economical manufacturing process and high yield, or a pharmaceutically acceptable salt thereof.
본 발명은 경제적인 제조공정과 높은 수율로 대량 생산이 가능한 (1R,2S)-1-(6-브로모-2-메톡시퀴놀린-3-일)-4-디메틸아미노-2-(1-나프틸)-1-페닐-부탄-2-올을 분리하는 방법을 포함하는 (1R,2S)-1-(6-브로모-2-메톡시퀴놀린-3-일)-4-디메틸아미노-2-(1-나프틸)-1-페닐-부탄-2-올 또는 이의 약제학적으로 허용 가능한 염의 제조방법에 관한 것이다. |
| format | Patent |
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본 발명은 경제적인 제조공정과 높은 수율로 대량 생산이 가능한 (1R,2S)-1-(6-브로모-2-메톡시퀴놀린-3-일)-4-디메틸아미노-2-(1-나프틸)-1-페닐-부탄-2-올을 분리하는 방법을 포함하는 (1R,2S)-1-(6-브로모-2-메톡시퀴놀린-3-일)-4-디메틸아미노-2-(1-나프틸)-1-페닐-부탄-2-올 또는 이의 약제학적으로 허용 가능한 염의 제조방법에 관한 것이다.</description><language>eng ; kor</language><subject>APPARATUS THEREFOR ; CHEMISTRY ; GENERAL METHODS OF ORGANIC CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2021</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210917&DB=EPODOC&CC=KR&NR=102303635B1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210917&DB=EPODOC&CC=KR&NR=102303635B1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>KIM JAEHAN</creatorcontrib><creatorcontrib>KIM YONG JIK</creatorcontrib><creatorcontrib>SHIN CHANG YONG</creatorcontrib><title>1R2S-1-6--2--3--4--2-1--1---2- PROCESS FOR PREPARING 1R2S-1-6-bromo-2-methoxyquinolin-3-yl-4-dimethylamino-2-1-naphthyl-1-phenyl-butan-2-ol AND PHARMACEUTICALLY ACCEPTABLE SALT</title><description>The present invention relates to a method for manufacturing (1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-4-dimethylamino-2-(1-naphthyl)-1-phenyl-butan-2-ol comprising a method for separating (1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-4-dimethylamino-2-(1-naphthyl)-1-phenyl-butan-2-ol capable of mass production with an economical manufacturing process and high yield, or a pharmaceutically acceptable salt thereof.
본 발명은 경제적인 제조공정과 높은 수율로 대량 생산이 가능한 (1R,2S)-1-(6-브로모-2-메톡시퀴놀린-3-일)-4-디메틸아미노-2-(1-나프틸)-1-페닐-부탄-2-올을 분리하는 방법을 포함하는 (1R,2S)-1-(6-브로모-2-메톡시퀴놀린-3-일)-4-디메틸아미노-2-(1-나프틸)-1-페닐-부탄-2-올 또는 이의 약제학적으로 허용 가능한 염의 제조방법에 관한 것이다.</description><subject>APPARATUS THEREFOR</subject><subject>CHEMISTRY</subject><subject>GENERAL METHODS OF ORGANIC CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2021</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjEGLwjAUhHvZw-L6HwJ7fmAa13sa061YtaTdg6cSNdJCmnS1gv1X_kRfRTwLD-ZjZt58BjeqwhwozABCAAYwHYDCcAgkUxsh85zEG4UsM64W61_yetqdfOOx15iu8tf-_1I7b2uHQ73FqUM9BL3VDfqPXafbanAQ28o4hN2l0w4zbwlfz0mWcLXiQv4VC8HTdEu4EDIreJRKkvO0-Ao-jtqezfipo-A7loVIwLS-NOdW740zXblUdBKyCZuxnyii7L3WHdaVTiI</recordid><startdate>20210917</startdate><enddate>20210917</enddate><creator>KIM JAEHAN</creator><creator>KIM YONG JIK</creator><creator>SHIN CHANG YONG</creator><scope>EVB</scope></search><sort><creationdate>20210917</creationdate><title>1R2S-1-6--2--3--4--2-1--1---2- PROCESS FOR PREPARING 1R2S-1-6-bromo-2-methoxyquinolin-3-yl-4-dimethylamino-2-1-naphthyl-1-phenyl-butan-2-ol AND PHARMACEUTICALLY ACCEPTABLE SALT</title><author>KIM JAEHAN ; KIM YONG JIK ; SHIN CHANG YONG</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_KR102303635BB13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; kor</language><creationdate>2021</creationdate><topic>APPARATUS THEREFOR</topic><topic>CHEMISTRY</topic><topic>GENERAL METHODS OF ORGANIC CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>KIM JAEHAN</creatorcontrib><creatorcontrib>KIM YONG JIK</creatorcontrib><creatorcontrib>SHIN CHANG YONG</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>KIM JAEHAN</au><au>KIM YONG JIK</au><au>SHIN CHANG YONG</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>1R2S-1-6--2--3--4--2-1--1---2- PROCESS FOR PREPARING 1R2S-1-6-bromo-2-methoxyquinolin-3-yl-4-dimethylamino-2-1-naphthyl-1-phenyl-butan-2-ol AND PHARMACEUTICALLY ACCEPTABLE SALT</title><date>2021-09-17</date><risdate>2021</risdate><abstract>The present invention relates to a method for manufacturing (1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-4-dimethylamino-2-(1-naphthyl)-1-phenyl-butan-2-ol comprising a method for separating (1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-4-dimethylamino-2-(1-naphthyl)-1-phenyl-butan-2-ol capable of mass production with an economical manufacturing process and high yield, or a pharmaceutically acceptable salt thereof.
본 발명은 경제적인 제조공정과 높은 수율로 대량 생산이 가능한 (1R,2S)-1-(6-브로모-2-메톡시퀴놀린-3-일)-4-디메틸아미노-2-(1-나프틸)-1-페닐-부탄-2-올을 분리하는 방법을 포함하는 (1R,2S)-1-(6-브로모-2-메톡시퀴놀린-3-일)-4-디메틸아미노-2-(1-나프틸)-1-페닐-부탄-2-올 또는 이의 약제학적으로 허용 가능한 염의 제조방법에 관한 것이다.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | APPARATUS THEREFOR CHEMISTRY GENERAL METHODS OF ORGANIC CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | 1R2S-1-6--2--3--4--2-1--1---2- PROCESS FOR PREPARING 1R2S-1-6-bromo-2-methoxyquinolin-3-yl-4-dimethylamino-2-1-naphthyl-1-phenyl-butan-2-ol AND PHARMACEUTICALLY ACCEPTABLE SALT |
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