1R2S-1-6--2--3--4--2-1--1---2- PROCESS FOR PREPARING 1R2S-1-6-bromo-2-methoxyquinolin-3-yl-4-dimethylamino-2-1-naphthyl-1-phenyl-butan-2-ol AND PHARMACEUTICALLY ACCEPTABLE SALT

The present invention relates to a method for manufacturing (1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-4-dimethylamino-2-(1-naphthyl)-1-phenyl-butan-2-ol comprising a method for separating (1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-4-dimethylamino-2-(1-naphthyl)-1-phenyl-butan-2-ol capable of mass p...

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Bibliographische Detailangaben
Hauptverfasser:	KIM JAEHAN, KIM YONG JIK, SHIN CHANG YONG
Format:	Patent
Sprache:	eng ; kor
Schlagworte:	APPARATUS THEREFOR CHEMISTRY GENERAL METHODS OF ORGANIC CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to a method for manufacturing (1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-4-dimethylamino-2-(1-naphthyl)-1-phenyl-butan-2-ol comprising a method for separating (1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-4-dimethylamino-2-(1-naphthyl)-1-phenyl-butan-2-ol capable of mass production with an economical manufacturing process and high yield, or a pharmaceutically acceptable salt thereof. 본 발명은 경제적인 제조공정과 높은 수율로 대량 생산이 가능한 (1R,2S)-1-(6-브로모-2-메톡시퀴놀린-3-일)-4-디메틸아미노-2-(1-나프틸)-1-페닐-부탄-2-올을 분리하는 방법을 포함하는 (1R,2S)-1-(6-브로모-2-메톡시퀴놀린-3-일)-4-디메틸아미노-2-(1-나프틸)-1-페닐-부탄-2-올 또는 이의 약제학적으로 허용 가능한 염의 제조방법에 관한 것이다.