NOVEL BIOMARKER FOR PREDICTING DRUG-RESPONSIBILITY TO COLON CANCER

The present invention relates to a novel biomarker composition for predicting susceptibility to anticancer drugs for colorectal cancer, and a method for providing information for predicting sensitivity to anticancer drugs in colorectal cancer using the same. The biomarker according to the present in...

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Bibliographische Detailangaben
Hauptverfasser: KIM TAE SOO, LEE YE EUN, CHO YOUNG WON, RYU KYUNG HYUN, KIM HWANG PHILL, WOO HYEONJU, CHOI HEY MI, KIM HYOUNG PYO, CHOI SUN SHIM, LEE MIN KYUNG
Format: Patent
Sprache:eng ; kor
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Zusammenfassung:The present invention relates to a novel biomarker composition for predicting susceptibility to anticancer drugs for colorectal cancer, and a method for providing information for predicting sensitivity to anticancer drugs in colorectal cancer using the same. The biomarker according to the present invention shows an excellent effect in predicting the sensitivity of anticancer drugs in colorectal cancer. Accordingly, the sensitivity of each patient can be reliably determined before the start of treatment, and it becomes possible to select an anticancer drug with high therapeutic effect. In addition, since the use of an anticancer drug for which an effect is not obtained can be avoided, unnecessary side effects can be avoided. 본 발명은 대장암에 대한 항암제 감수성 예측을 위한 신규 바이오마커 조성물, 이를 이용한 대장암에서 항암제의 감수성 예측을 위한 정보 제공 방법에 관한 것이다. 본 발명에 따른 바이오마커는 대장암에서 항암제의 감수성 예측에 우수한 효과를 보인다. 이에 따라, 개개의 환자의 상기 감수성을 치료 개시 전에 확실하게 판정할 수 있어, 치료 효과가 높은 항암제의 선택이 가능해진다. 또한, 효과가 얻어지지 않는 항암제의 사용을 회피할 수 있기 때문에 불필요한 부작용을 회피할 수 있다.