Novel intercalating fluorescent dyes for labelling nucleic acids and the preparation method thereof

The present invention relates to a novel intercalating fluorescent compound for analyzing nucleic acids and the like which has excellent intercalation efficiency of biomaterials with nucleic acids such as DNA and RNA, continuously maintains the fluorescence properties and efficiency, and shows excel...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	SI HO YOUNG, JEONG EUNAE, HYUNG JUN YOON, JANG SU JUNG, PARK JIN WOO
Format:	Patent
Sprache:	eng ; kor
Schlagworte:	ADHESIVES BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES DYES ENZYMOLOGY HUMAN NECESSITIES HYGIENE LAKES MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MISCELLANEOUS APPLICATIONS OF MATERIALS MISCELLANEOUS COMPOSITIONS MORDANTS MUTATION OR GENETIC ENGINEERING NATURAL RESINS ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES PAINTS POLISHES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS VINEGAR WINE
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The present invention relates to a novel intercalating fluorescent compound for analyzing nucleic acids and the like which has excellent intercalation efficiency of biomaterials with nucleic acids such as DNA and RNA, continuously maintains the fluorescence properties and efficiency, and shows excellent effects in terms of storage stability such as temperature and moisture and biosafety. In addition, the fluorescent compound of the present invention can be dissolved in distilled water, a solvent harmless to the human body, and can be applied to a wide range of analysis without being limited to the analysis of specific cells and living tissues. 본 발명의 핵산 등을 분석하기 위한 신규한 인터컬레이팅 형광 화합물은 생체물질의 DNA, RNA 등의 핵산과의 인터컬레이팅 효율이 매우 우수하고, 아울러 형광 특성 및 효율을 지속적으로 유지할 수 있을 뿐만 아니라, 온도 및 수분 등의 보관 안정성 및 생체안전성 측면에서도 뛰어난 효과를 나타낸다. 또한, 본 발명의 형광 화합물은 인체에 무해한 용매인 증류수에 용해가 가능하고 특정 세포 및 생체조직의 분석에 국한되지 않고 넓은 범위의 분석에 응용할 수 있다는 다양한 장점이 있다.