PCR Method kits and PCR device for detecting methylation of gene using reduction probe

The present invention relates to a method, kit, and PCR device for detecting the methylation of a gene using a reduction probe. The present invention can detect methylation of genes without treating bisulfite or methylation specific enzymes, thereby being simple and having good sensitivity and accur...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: LEE HAN WOO, PARK HEE KYUNG, JEON MEE HYANG, CHINBAYAR BAT OCHIR, YOON KYUNG JU
Format: Patent
Sprache:eng ; kor
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Beschreibung
Zusammenfassung:The present invention relates to a method, kit, and PCR device for detecting the methylation of a gene using a reduction probe. The present invention can detect methylation of genes without treating bisulfite or methylation specific enzymes, thereby being simple and having good sensitivity and accuracy in detection and being useful in various disease diagnosis fields including cancer. 본 발명은 리덕션 프로브를 이용한 유전자의 메틸화 검출 방법, 검출 키트 및 PCR 장치에 관한 것으로서, 바이설파이트 또는 메틸화 특이적 효소를 처리하지 않고도 유전자의 메틸화를 검출할 수 있어 간편하고, 우수한 민감도 및 정확도로 검출할 수 있어 암을 포함한 다양한 질병 진단 분야에서 유용하다.