Anti-inflammatory composition comprising pepper leaf extract produced by enzyme treatment as effective component

The present invention relates to an anti-inflammatory composition comprising, as an active ingredient, a Capsicum annuum leaf extract obtained by enzyme treatment. More particularly, an extraction yield and the total polyphenol content of the Capsicum annuum leaf extract treated with a commercial en...

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Bibliographische Detailangaben
Hauptverfasser: AHN GIL SOO, LEE HYOEN HWA, KIM MIN JO, KIM TAEWAN, MA YUMI, NAM SUKYUNG, KWEON GI JUN, JO KUK YOUNG, LEE HYEMIN, SON YERIM, BAE KYUNG MI
Format: Patent
Sprache:eng ; kor
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Zusammenfassung:The present invention relates to an anti-inflammatory composition comprising, as an active ingredient, a Capsicum annuum leaf extract obtained by enzyme treatment. More particularly, an extraction yield and the total polyphenol content of the Capsicum annuum leaf extract treated with a commercial enzyme, called Pectinex are increased compared to an ethanol extract of the Capsicum annuum leaf, and as the extract is excellent in inhibiting the production of NO induced by LPS, the composition of the present invention can be used as a functional cosmetic product and a functional health food for preventing or ameliorating inflammation or a therapeutic agent for inflammation. A manufacturing method of the anti-inflammatory composition comprises the steps of: manufacturing Capsicum annuum leaf powder; hydrolyzing the same after adding Pectinex; and treating the hydrolysate with ethanol. 본 발명은 효소처리를 통해 얻은 고춧잎 추출물을 유효성분으로 함유하는 항염증용 조성물에 관한 것으로, 더욱 상세하게는 상업용 효소인 펙티넥스(Pectinex)를 처리한 고춧잎 추출물의 추출수율 및 총 폴리페놀 함량은 고춧잎 에탄올 추출물에 비해 증가하고, 상기 추출물은 LPS에 의해 유도된 NO 생성을 억제하는 효과가 우수하므로 염증의 예방 또는 개선용 건강기능식품, 기능성 화장품 또는 염증의 치료제로 사용될 수 있다.