SE1 Novel Salmonella specific bacteriophage SE1 and antibacterial composition comprising the same

The present invention relates to a novel bacteriophage SE1 which is specific to salmonella and has a killing function; a pharmaceutical composition, an antibiotic composition, a feed additive composition, a feed, a disinfectant, or a washing agent which is for preventing or treating infectious disea...

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Bibliographische Detailangaben
Hauptverfasser:	KIM, HYUN IL, PARK, CHARL SE, KIM, YOUNG JU, YEON, YOUNG EUN, HAN, BEOM KU, JANG, BONG GEUN
Format:	Patent
Sprache:	eng ; kor
Schlagworte:	ANIMAL AND VEGETABLE OILS, FATS, FATTY SUBSTANCES AND WAXES BEER BIOCHEMISTRY CANDLES CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA DETERGENT COMPOSITIONS DETERGENTS DISINFECTION, STERILISATION, OR DEODORISATION OF AIR ENZYMOLOGY FATTY ACIDS THEREFROM FODDER FOODS OR FOODSTUFFS HUMAN NECESSITIES HYGIENE MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES MEDICAL OR VETERINARY SCIENCE METALLURGY METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS RECOVERY OF GLYCEROL RESIN SOAPS SOAP OR SOAP-MAKING SPIRITS THEIR TREATMENT, NOT COVERED BY OTHER CLASSES USE OF SINGLE SUBSTANCES AS DETERGENTS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention relates to a novel bacteriophage SE1 which is specific to salmonella and has a killing function; a pharmaceutical composition, an antibiotic composition, a feed additive composition, a feed, a disinfectant, or a washing agent which is for preventing or treating infectious diseases caused by salmonella and includes the bacteriophage; and a method for preventing or treating infectious diseases caused by salmonella, wherein the method comprises a step of administrating the bacteriophage to an animal. According to the present invention, a method for preventing or treating infectious diseases caused by salmonella by using bacteriophage SE1 has very high specificity to salmonella compared to a conventional chemical material such as antibiotics or the like, and the bacteriophage SE1 is infected to salmonella to proliferate 100 times or more in the salmonella, thereby having excellent bacteriolytic activity and being strong to physiochemical stimulation. In addition, the bacteriophage SE1 of the present invention is not infected to a host, such as a human, an animal, or a plant, other than bacteria, and thus a problem of antibiotic resistant bacteria due to the abuse of antibiotics, a problem of residual antibiotics in food, and a problem of a wide range of host ranges can be solved. Accordingly, the bacteriophage SE1 of the present invention can be variously used in the fields of prevention or treatment of infectious diseases caused by salmonella, antibiotic compositions, feed additive compositions, feeds, disinfectants, or washing agents. 본 발명은 살모넬라균에 특이적인 사멸능을 갖는 신규 박테리오파지 SE1, 상기 박테리오파지를 포함하는 살모넬라균에 의한 감염성 질병의 예방 또는 치료용 약학적 조성물, 항생용 조성물, 사료 첨가용 조성물, 사료, 소독제 또는 세척제 및 상기 박테리오파지를 동물에 투여하는 단계를 포함하는 살모넬라균에 의한 감염성 질병의 예방 또는 치료 방법에 관한 것이다. 본 발명의 박테리오파지 SE1을 이용한 살모넬라균에 의한 감염성 질병의 예방 또는 치료 방법은 기존의 항생제 등의 화학물질에 비해 살모넬라균에 대한 특이성이 매우 높고, 상기 박테리오파지 SE1은 살모넬라에 감염하여 살모넬라 내에서 100배 이상 증식함으로써 용균 활성이 우수하고 물리화학적 자극에 강하다는 장점을 가지고 있다. 또한 본 발명의 박테리오파지 SE1은 사람, 동물, 식물 등 세균외의 다른 숙주에는 감염되지 않으므로, 항생제의 오남용으로 인한 항생제 내성균의 문제점, 식품 내의 항생제의 잔류 문제, 광범위한 숙주범위의 문제점을 해결할 수 있는 장점이 있다. 따라서, 본 발명의 박테리오파지 SE1은 살모넬라균에 의한 감염성 질병의 예방 또는 치료, 항생용 조성물, 사료 첨가용 조성물, 사료, 소독제, 또는 세척제 분야에서 다양하게 사용될 수 있다.