MGLUR5 RADIOTRACER COMPOSITION

The present invention relates to a radioactive composition comprising a radioactivity-marked quinoline compound [^11C]. The quinolone compound [^11C] of the present invention is useful as a radioactive ligand which is specifically bonded with respect to mGluR5, and is useful as an imaging agent for...

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Bibliographische Detailangaben
Hauptverfasser: MOON, BYUNG SEOK, LEE, HO YOUNG, SON, MYUNG HEE, PAE, AE NIM, LEE, BYUNG CHUL, MIN, SUN JOON, CHOO, HYUN AH, KEUM, GYO CHANG, PARK, KI DUK, KIM, JI YEONG, LEE, JAE KYUN, CHO, YONG SEO
Format: Patent
Sprache:eng ; kor
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Zusammenfassung:The present invention relates to a radioactive composition comprising a radioactivity-marked quinoline compound [^11C]. The quinolone compound [^11C] of the present invention is useful as a radioactive ligand which is specifically bonded with respect to mGluR5, and is useful as an imaging agent for progressing or relieving diseases derived from overexpression of mGluR5. 본 발명은 방사성 표지된 [C]퀴놀린 화합물이 포함된 방사성 조성물에 관한 것이다. 본 발명의 [C]퀴놀린 화합물은 mGluR5에 대하여 특이적으로 결합 결합하는 방사성 리간드로 유용하므로, mGluR5의 과다 발현으로 유래된 질환의 진행 또는 완화를 모니터링하기 위한 영상화제로 유용하다.