A SOLUBILITY-ENHANCED PHARMACEUTICAL FORMULATION COMPRISING SILODOSIN

The present invention relates to a pharmaceutical formulation and a producing method thereof, comprising a solid dispersion formed by making silicon dioxide adsorb silodosin or a pharmaceutically acceptable salt thereof. The silodosin or the pharmaceutically acceptable salt thereof and povidone are...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: JUNG, KWANG DON, JI, HYUN KU, KIM, IN SU
Format: Patent
Sprache:eng ; kor
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Beschreibung
Zusammenfassung:The present invention relates to a pharmaceutical formulation and a producing method thereof, comprising a solid dispersion formed by making silicon dioxide adsorb silodosin or a pharmaceutically acceptable salt thereof. The silodosin or the pharmaceutically acceptable salt thereof and povidone are mixed at the ratio of 1 : 0.5 to 2 parts by weight, and elution properties of silodosin can be improved. 본 발명은 실로도신 또는 이의 약학적으로 허용가능한 염이 이산화규소에 흡착되어 형성된 고체 분산체를 포함하는 약제학적 제제 및 이의 제조방법에 관한 것으로, 실로도신의 용출 특성이 향상되는 효과가 있다.