PHARMACEUTICAL COMPOSITION WITH IMPROVED STABILITY COMPRISING AN ACTIVE INGREDIENT DERIVED FROM HERBAL SUBSTANCES
The present invention relates to a pharmaceutical composition comprising a herbal medicine extract of Clematis florida, Trichosanthis radix and Prunella vulgaris var. lilacina Nakai and a stabilizer and, specifically, the stability of active ingredients in a herbal medicine extract of Clematis flori...
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| creator | SHIN, HO CHUL KIM, HUN TAEK PARK, YEO JIN SHIN, DONG CHUL KIM, WOONG SIK PARK, JAE HONG RHEE, HAE IN |
| description | The present invention relates to a pharmaceutical composition comprising a herbal medicine extract of Clematis florida, Trichosanthis radix and Prunella vulgaris var. lilacina Nakai and a stabilizer and, specifically, the stability of active ingredients in a herbal medicine extract of Clematis florida, Trichosanthis radix and Prunella vulgaris var. lilacina Nakai is greatly increased using cellulose, a derivative thereof or a polymer comprising a pyrrolidone functional group as a stabilizer. Therefore, a drug comprising a high content of an active ingredient with increased stability can be produced when using the stabilizer of the present invention.
본 발명은 위령선, 괄루근 및 하고초의 생약 추출물 및 안정화제를 포함하는 약학적 조성물에 대한 것으로, 구체적으로 안정화제로 셀룰로스 또는 그의 유도체, 또는 피롤리돈 기능기를 포함하는 중합체를 사용하면, 위령선, 괄루근 및 하고초의 생약 추출물의 유효 성분의 안정성이 크게 증가한다. 따라서, 본 발명의 안정화제를 이용시 안정성이 증가된 유효 성분을 고함량으로 포함하는 약물을 제조할 수 있다. |
| format | Patent |
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본 발명은 위령선, 괄루근 및 하고초의 생약 추출물 및 안정화제를 포함하는 약학적 조성물에 대한 것으로, 구체적으로 안정화제로 셀룰로스 또는 그의 유도체, 또는 피롤리돈 기능기를 포함하는 중합체를 사용하면, 위령선, 괄루근 및 하고초의 생약 추출물의 유효 성분의 안정성이 크게 증가한다. 따라서, 본 발명의 안정화제를 이용시 안정성이 증가된 유효 성분을 고함량으로 포함하는 약물을 제조할 수 있다.</description><language>eng ; kor</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2015</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20151020&DB=EPODOC&CC=KR&NR=101561818B1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20151020&DB=EPODOC&CC=KR&NR=101561818B1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>SHIN, HO CHUL</creatorcontrib><creatorcontrib>KIM, HUN TAEK</creatorcontrib><creatorcontrib>PARK, YEO JIN</creatorcontrib><creatorcontrib>SHIN, DONG CHUL</creatorcontrib><creatorcontrib>KIM, WOONG SIK</creatorcontrib><creatorcontrib>PARK, JAE HONG</creatorcontrib><creatorcontrib>RHEE, HAE IN</creatorcontrib><title>PHARMACEUTICAL COMPOSITION WITH IMPROVED STABILITY COMPRISING AN ACTIVE INGREDIENT DERIVED FROM HERBAL SUBSTANCES</title><description>The present invention relates to a pharmaceutical composition comprising a herbal medicine extract of Clematis florida, Trichosanthis radix and Prunella vulgaris var. lilacina Nakai and a stabilizer and, specifically, the stability of active ingredients in a herbal medicine extract of Clematis florida, Trichosanthis radix and Prunella vulgaris var. lilacina Nakai is greatly increased using cellulose, a derivative thereof or a polymer comprising a pyrrolidone functional group as a stabilizer. Therefore, a drug comprising a high content of an active ingredient with increased stability can be produced when using the stabilizer of the present invention.
본 발명은 위령선, 괄루근 및 하고초의 생약 추출물 및 안정화제를 포함하는 약학적 조성물에 대한 것으로, 구체적으로 안정화제로 셀룰로스 또는 그의 유도체, 또는 피롤리돈 기능기를 포함하는 중합체를 사용하면, 위령선, 괄루근 및 하고초의 생약 추출물의 유효 성분의 안정성이 크게 증가한다. 따라서, 본 발명의 안정화제를 이용시 안정성이 증가된 유효 성분을 고함량으로 포함하는 약물을 제조할 수 있다.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2015</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjEEKwjAQRbtxIeodBlwLBlHcJunUDDZJmaQVV6VIXIlW6v2xigdw9fnw3ptmz8pItlJjHUnLErS3lQ8UyTs4UTRAtmLfYA4hSkUlxfOXYQrkDiAdSB2pQRgfY07oIuTI9DEK9hYMshq7oVZjwGkM82xy7W5DWvx2li0LjNqsUv9o09B3l3RPr_bIYi22O7EXe6XE5j_qDUh6OZc</recordid><startdate>20151020</startdate><enddate>20151020</enddate><creator>SHIN, HO CHUL</creator><creator>KIM, HUN TAEK</creator><creator>PARK, YEO JIN</creator><creator>SHIN, DONG CHUL</creator><creator>KIM, WOONG SIK</creator><creator>PARK, JAE HONG</creator><creator>RHEE, HAE IN</creator><scope>EVB</scope></search><sort><creationdate>20151020</creationdate><title>PHARMACEUTICAL COMPOSITION WITH IMPROVED STABILITY COMPRISING AN ACTIVE INGREDIENT DERIVED FROM HERBAL SUBSTANCES</title><author>SHIN, HO CHUL ; KIM, HUN TAEK ; PARK, YEO JIN ; SHIN, DONG CHUL ; KIM, WOONG SIK ; PARK, JAE HONG ; RHEE, HAE IN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_KR101561818BB13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; kor</language><creationdate>2015</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>SHIN, HO CHUL</creatorcontrib><creatorcontrib>KIM, HUN TAEK</creatorcontrib><creatorcontrib>PARK, YEO JIN</creatorcontrib><creatorcontrib>SHIN, DONG CHUL</creatorcontrib><creatorcontrib>KIM, WOONG SIK</creatorcontrib><creatorcontrib>PARK, JAE HONG</creatorcontrib><creatorcontrib>RHEE, HAE IN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>SHIN, HO CHUL</au><au>KIM, HUN TAEK</au><au>PARK, YEO JIN</au><au>SHIN, DONG CHUL</au><au>KIM, WOONG SIK</au><au>PARK, JAE HONG</au><au>RHEE, HAE IN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>PHARMACEUTICAL COMPOSITION WITH IMPROVED STABILITY COMPRISING AN ACTIVE INGREDIENT DERIVED FROM HERBAL SUBSTANCES</title><date>2015-10-20</date><risdate>2015</risdate><abstract>The present invention relates to a pharmaceutical composition comprising a herbal medicine extract of Clematis florida, Trichosanthis radix and Prunella vulgaris var. lilacina Nakai and a stabilizer and, specifically, the stability of active ingredients in a herbal medicine extract of Clematis florida, Trichosanthis radix and Prunella vulgaris var. lilacina Nakai is greatly increased using cellulose, a derivative thereof or a polymer comprising a pyrrolidone functional group as a stabilizer. Therefore, a drug comprising a high content of an active ingredient with increased stability can be produced when using the stabilizer of the present invention.
본 발명은 위령선, 괄루근 및 하고초의 생약 추출물 및 안정화제를 포함하는 약학적 조성물에 대한 것으로, 구체적으로 안정화제로 셀룰로스 또는 그의 유도체, 또는 피롤리돈 기능기를 포함하는 중합체를 사용하면, 위령선, 괄루근 및 하고초의 생약 추출물의 유효 성분의 안정성이 크게 증가한다. 따라서, 본 발명의 안정화제를 이용시 안정성이 증가된 유효 성분을 고함량으로 포함하는 약물을 제조할 수 있다.</abstract><oa>free_for_read</oa></addata></record> |
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| title | PHARMACEUTICAL COMPOSITION WITH IMPROVED STABILITY COMPRISING AN ACTIVE INGREDIENT DERIVED FROM HERBAL SUBSTANCES |
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