PHARMACEUTICAL COMPOSITION WITH IMPROVED STABILITY COMPRISING AN ACTIVE INGREDIENT DERIVED FROM HERBAL SUBSTANCES

The present invention relates to a pharmaceutical composition comprising a herbal medicine extract of Clematis florida, Trichosanthis radix and Prunella vulgaris var. lilacina Nakai and a stabilizer and, specifically, the stability of active ingredients in a herbal medicine extract of Clematis flori...

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Bibliographische Detailangaben
Hauptverfasser:	SHIN, HO CHUL, KIM, HUN TAEK, PARK, YEO JIN, SHIN, DONG CHUL, KIM, WOONG SIK, PARK, JAE HONG, RHEE, HAE IN
Format:	Patent
Sprache:	eng ; kor
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to a pharmaceutical composition comprising a herbal medicine extract of Clematis florida, Trichosanthis radix and Prunella vulgaris var. lilacina Nakai and a stabilizer and, specifically, the stability of active ingredients in a herbal medicine extract of Clematis florida, Trichosanthis radix and Prunella vulgaris var. lilacina Nakai is greatly increased using cellulose, a derivative thereof or a polymer comprising a pyrrolidone functional group as a stabilizer. Therefore, a drug comprising a high content of an active ingredient with increased stability can be produced when using the stabilizer of the present invention. 본 발명은 위령선, 괄루근 및 하고초의 생약 추출물 및 안정화제를 포함하는 약학적 조성물에 대한 것으로, 구체적으로 안정화제로 셀룰로스 또는 그의 유도체, 또는 피롤리돈 기능기를 포함하는 중합체를 사용하면, 위령선, 괄루근 및 하고초의 생약 추출물의 유효 성분의 안정성이 크게 증가한다. 따라서, 본 발명의 안정화제를 이용시 안정성이 증가된 유효 성분을 고함량으로 포함하는 약물을 제조할 수 있다.