NEW COMPOUNDS HAVING SKIN WHITENING AND PPAR ACTIVITY, AND MEDICAL USE THEREOF

PURPOSE: A novel compound with whitening effect and peroxisome proliferator-activated receptor (PPAR) activity is provided to ensure skin whitening activity by suppressing tyrosinase, and to be used in a pharmaceutical composition or a cosmetic product for skin whitening, and as a pharmaceutical composition or a health functional food for preventing and treating obesity, metabolic diseases, or cardiovascular diseases. CONSTITUTION: A compound is denoted by chemical formula 1. A skin whitening composition contains the compound of chemical formula 1 as an active ingredient. The compound is selected from the group consisting of 2- (2,4-dihydroxyphenyl)-5,6- (methylenedioxy)-benzothiazole, 2- (3-methoxy-4-hydroxyphenyl)-5,6- (methylenedioxy)-benzothiazole, 4- (6,7-dihydro-5H-indeno[5,6-d]thiazol-2-yl)benzene-1,3-diol, 5- (6,7-dihydro-5H-indeno[5,6-d]thiazol-2-yl)-2-methoxyphenol, and bromo-4- (6,7-dihydro-5H-indeno[5,6-d]thiazol-2-yl)phenol. A pharmaceutical composition for preventing or treating one disease selected among obesity, metabolic diseases, and cardiovascular diseases contains the compound of chemical formula 1 as an active ingredient, and is regulated by PPAR activity. The PPAR is PPAR alpha or PPAR gamma.