NOVEL SYNTHESIZING METHOD FOR XANTHORRIHIZOL
A synthesizing method for xanthorrihizol is provided to prepare xanthorrhizol with high purity and high yield while simplifying a process and to prevent the generation of contaminants like heavy metals. A synthesizing method for xanthorrihizol indicated as the chemical formula VII comprises (a) a st...
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Zusammenfassung: | A synthesizing method for xanthorrihizol is provided to prepare xanthorrhizol with high purity and high yield while simplifying a process and to prevent the generation of contaminants like heavy metals. A synthesizing method for xanthorrihizol indicated as the chemical formula VII comprises (a) a step for synthesizing a compound of the chemical formula II by reacting a compound of the following chemical formula I with a Grignard reagent; (b) a step for synthesizing a compound of the chemical formula III by dehydrating the synthesized compound of the chemical formula II; (c) a step for synthesizing a compound of the compound IV by oxidizing and reducing the synthesized compound of the chemical formula III; (d) a step for synthesizing a compound of the compound V by reacting a compound of the chemical formula IV with a nucleophilic source, wherein the nucleophilic source is selected from the group consisting of halogen acid, sulfonic acid, sulfonic acid anhydride and sulfonic acid halide; (e) astep for synthesizing the compound of the chemical formula VI by reacting a compound of the chemical formula V with an Grignard reagent in the presence of a catalyst; and (f) a step for synthesizing a compound of the chemical formula VII by reacting the compound of the chemical formula VI with a substrate, wherein the substrate is selected from the group consisting of boron tribromide(BBr3), L-selectlide, trimethylboron bromide(Me2BBr) boron, trifluoride, diethylether mixture (BF3.Et2O) and ethylenedithiol. |
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