ORAL COMPOSITION CONTAINING EXTRACT OF ULMI CORTEX FOR TREATMENT OF PERIODONTAL DISEASES

PURPOSE: Provided is an oral composition containing Ulmi Cortex extract, Achyranthes japonica extract or the mixture thereof for treatment of periodontal diseases. It inhibits the generation of superoxide, PGE2, interleukin-1 beta, as well as collagenase, while promoting the synthesis of collagen pr...

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Bibliographische Detailangaben
Hauptverfasser: SUK, JAE GYUN, CHOI, GYEONG CHEOL, KIM, MUN MU, KIM, SANG NYEON
Format: Patent
Sprache:eng ; kor
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Zusammenfassung:PURPOSE: Provided is an oral composition containing Ulmi Cortex extract, Achyranthes japonica extract or the mixture thereof for treatment of periodontal diseases. It inhibits the generation of superoxide, PGE2, interleukin-1 beta, as well as collagenase, while promoting the synthesis of collagen protein. CONSTITUTION: An oral composition for treatment of periodontal diseases is characterized by containing Ulmi Cortex extract which is obtained by using an extract solvent selected from the group consisting of water, methanol, ethanol, propanol and butanol, in the amount of 0.01-5 wt.%. It further contains Achyranthes japonica extract. 본 발명은 치주질환 유발물질인 슈퍼옥사이드(superoxide), 프로스타글란딘(PGE), 인터루킨-1β(interleukin-1β)의 생성을 억제할 뿐 아니라, 치주조직의 기질인 콜라겐 단백질을 분해하는 콜라게나제(collagenase) 효소의 활성을 억제시킴과 동시에 콜라겐 단백질합성을 촉진시킴으로써 치주질환을 효과적으로 치료할 수 있는 우슬 추출물, 유백피 추출물 또는 이들의 혼합물을 함유한 구강용 조성물에 관한 것이다.