INCLUSION COMPOUNDS OF NIMESULIDE WITH CYCLODEXTRINS, PROCESS FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME

INCLUSION COMPOUNDS OF NIMESULIDE WITH CYCLODEXTRINS, PROCESS FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME

용해도가 높고 니메설리드 자체보다 더 신속하게 흡수되고/되거나 내독성이 보다 우수하며 사이클로덱스트린에 대한 니메설리드의 몰 비가 1:0.5 내지 1:15인, 니메설리드와 사이클로덱스트린과의 포접 화합물. Inclusion compounds of nimesulide with cyclodextrins, in the molar ratio of nimesulide to cyclodextrin comprised between 1:0.5 and 1:15, which possess high solubility and are more rapid...

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Bibliographische Detailangaben
Hauptverfasser: BIETTI, GUISEPPE, VIDI, ALDO, DUBIN, ENRICA, MAFFIONE, GRAZIA
Format: Patent
Sprache:eng ; kor
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:용해도가 높고 니메설리드 자체보다 더 신속하게 흡수되고/되거나 내독성이 보다 우수하며 사이클로덱스트린에 대한 니메설리드의 몰 비가 1:0.5 내지 1:15인, 니메설리드와 사이클로덱스트린과의 포접 화합물. Inclusion compounds of nimesulide with cyclodextrins, in the molar ratio of nimesulide to cyclodextrin comprised between 1:0.5 and 1:15, which possess high solubility and are more rapidly absorbed and/or better tolerated than nimesulide itself.