STABILIZED INJECTION AND METHOD OF STABILIZING INJECTION

STABILIZED INJECTION AND METHOD OF STABILIZING INJECTION

A stabilized injection comprising (+/-)-6-chloro-3,4-dihydro-4-methyl-3-oxo-N-quinuclidinyl-2H-1,4-benzoxazine-8-carboxamide monohydrochloride as the active ingredient and containing a light stabilizer. The coloration can be inhibited by using at least one light stabilizer selected from the group co...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: SHIBATA, TOSHIYUKI, HAMASAKI, TOSHIO, KINO, SHIGEMI, KAKITA, TAKESHI
Format: Patent
Sprache:eng
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:A stabilized injection comprising (+/-)-6-chloro-3,4-dihydro-4-methyl-3-oxo-N-quinuclidinyl-2H-1,4-benzoxazine-8-carboxamide monohydrochloride as the active ingredient and containing a light stabilizer. The coloration can be inhibited by using at least one light stabilizer selected from the group consisting of sulfurous acid and salts thereof, ascorbic acid salts, L-cystein and acid-addition salts thereof, thioglycolic acid and metallic salts thereof, ethylenediamine, salicyclic acid and salts thereof, and phenol and derivatives thereof.