TETREHYDROISOQUINOLINYLCARBAMATES OF 1,2,3,3A,8,8A-HEXAHYDRO-1,3A,8-TRIMETHYLPYRROLO(2,3,-6)INDOLE

상기 식(Ⅰ)의 1, 2, 3, 3a, 8, 8a-헥사히드로1, 3a, 8-트리메틸피롤로[2, 3-b]인돌의 테트라히드로이소퀴놀리닐 카바메이트(상기 식에서, R은 수소 또는 저급알킬이고, X는 수소이다)가 개시되며, 이 화합물은 콜린작용 결핍으로 특징되는 기억 기능장애를 경감시키는데 유용하다. There are disclosed tetrahydroisoquinolinylcarbamates of 1,2,3,3a,8,8a-hexahydro-1,3a,8-trimethylpyrrolo[2,3-b]indole of formula (I), w...

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Hauptverfasser: HAMER, RUSSELL RICHARD LEE, GLAMKOWSKI, EDWARD JOSEPH, KURYS, BARBARA ELAINE, FREED, BRIAN SCOTT, CHIANG, YULIN, HELSLEY, GROVER CLEVELAND
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creator HAMER, RUSSELL RICHARD LEE
GLAMKOWSKI, EDWARD JOSEPH
KURYS, BARBARA ELAINE
FREED, BRIAN SCOTT
CHIANG, YULIN
HELSLEY, GROVER CLEVELAND
description 상기 식(Ⅰ)의 1, 2, 3, 3a, 8, 8a-헥사히드로1, 3a, 8-트리메틸피롤로[2, 3-b]인돌의 테트라히드로이소퀴놀리닐 카바메이트(상기 식에서, R은 수소 또는 저급알킬이고, X는 수소이다)가 개시되며, 이 화합물은 콜린작용 결핍으로 특징되는 기억 기능장애를 경감시키는데 유용하다. There are disclosed tetrahydroisoquinolinylcarbamates of 1,2,3,3a,8,8a-hexahydro-1,3a,8-trimethylpyrrolo[2,3-b]indole of formula (I), where R is hydrogen or loweralkyl; and X is hydrogen, loweralkyl, halogen, loweralkoxy or hydroxy, which compounds being useful for alleviating memory dysfunctions characterized by a cholinergic deficit.
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There are disclosed tetrahydroisoquinolinylcarbamates of 1,2,3,3a,8,8a-hexahydro-1,3a,8-trimethylpyrrolo[2,3-b]indole of formula (I), where R is hydrogen or loweralkyl; and X is hydrogen, loweralkyl, halogen, loweralkoxy or hydroxy, which compounds being useful for alleviating memory dysfunctions characterized by a cholinergic deficit.</description><edition>6</edition><language>eng ; kor</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>1999</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19990201&amp;DB=EPODOC&amp;CC=KR&amp;NR=0172971B1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19990201&amp;DB=EPODOC&amp;CC=KR&amp;NR=0172971B1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>HAMER, RUSSELL RICHARD LEE</creatorcontrib><creatorcontrib>GLAMKOWSKI, EDWARD JOSEPH</creatorcontrib><creatorcontrib>KURYS, BARBARA ELAINE</creatorcontrib><creatorcontrib>FREED, BRIAN SCOTT</creatorcontrib><creatorcontrib>CHIANG, YULIN</creatorcontrib><creatorcontrib>HELSLEY, GROVER CLEVELAND</creatorcontrib><title>TETREHYDROISOQUINOLINYLCARBAMATES OF 1,2,3,3A,8,8A-HEXAHYDRO-1,3A,8-TRIMETHYLPYRROLO(2,3,-6)INDOLE</title><description>상기 식(Ⅰ)의 1, 2, 3, 3a, 8, 8a-헥사히드로1, 3a, 8-트리메틸피롤로[2, 3-b]인돌의 테트라히드로이소퀴놀리닐 카바메이트(상기 식에서, R은 수소 또는 저급알킬이고, X는 수소이다)가 개시되며, 이 화합물은 콜린작용 결핍으로 특징되는 기억 기능장애를 경감시키는데 유용하다. 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There are disclosed tetrahydroisoquinolinylcarbamates of 1,2,3,3a,8,8a-hexahydro-1,3a,8-trimethylpyrrolo[2,3-b]indole of formula (I), where R is hydrogen or loweralkyl; and X is hydrogen, loweralkyl, halogen, loweralkoxy or hydroxy, which compounds being useful for alleviating memory dysfunctions characterized by a cholinergic deficit.</abstract><edition>6</edition><oa>free_for_read</oa></addata></record>
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title TETREHYDROISOQUINOLINYLCARBAMATES OF 1,2,3,3A,8,8A-HEXAHYDRO-1,3A,8-TRIMETHYLPYRROLO(2,3,-6)INDOLE
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