TETREHYDROISOQUINOLINYLCARBAMATES OF 1,2,3,3A,8,8A-HEXAHYDRO-1,3A,8-TRIMETHYLPYRROLO(2,3,-6)INDOLE

상기 식(Ⅰ)의 1, 2, 3, 3a, 8, 8a-헥사히드로1, 3a, 8-트리메틸피롤로[2, 3-b]인돌의 테트라히드로이소퀴놀리닐 카바메이트(상기 식에서, R은 수소 또는 저급알킬이고, X는 수소이다)가 개시되며, 이 화합물은 콜린작용 결핍으로 특징되는 기억 기능장애를 경감시키는데 유용하다. There are disclosed tetrahydroisoquinolinylcarbamates of 1,2,3,3a,8,8a-hexahydro-1,3a,8-trimethylpyrrolo[2,3-b]indole of formula (I), w...

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Bibliographische Detailangaben
Hauptverfasser:	HAMER, RUSSELL RICHARD LEE, GLAMKOWSKI, EDWARD JOSEPH, KURYS, BARBARA ELAINE, FREED, BRIAN SCOTT, CHIANG, YULIN, HELSLEY, GROVER CLEVELAND
Format:	Patent
Sprache:	eng ; kor
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:	상기 식(Ⅰ)의 1, 2, 3, 3a, 8, 8a-헥사히드로1, 3a, 8-트리메틸피롤로[2, 3-b]인돌의 테트라히드로이소퀴놀리닐 카바메이트(상기 식에서, R은 수소 또는 저급알킬이고, X는 수소이다)가 개시되며, 이 화합물은 콜린작용 결핍으로 특징되는 기억 기능장애를 경감시키는데 유용하다. There are disclosed tetrahydroisoquinolinylcarbamates of 1,2,3,3a,8,8a-hexahydro-1,3a,8-trimethylpyrrolo[2,3-b]indole of formula (I), where R is hydrogen or loweralkyl; and X is hydrogen, loweralkyl, halogen, loweralkoxy or hydroxy, which compounds being useful for alleviating memory dysfunctions characterized by a cholinergic deficit.