IMIDAZOTHIADIAZINE DERIVATIVE AND PRODUCTION THEREOF

NEW MATERIAL:The 1,3,6,7-tetrahydro-7-oxo-imidazo[4,5-C][1,2,6]thiadiazine 2-oxide derivative of formula I [R1, R2 and R4 are (substituted)alkyl, aryl or aralkyl; R3 is H, halogen, (substituted)alkyl, (substituted)aryl or (substituted) aralkyl]. EXAMPLE:1-Hexyl-1,3,6,7-tetrahydro-3,6-dimethyl-7-oxo-...

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Hauptverfasser:	KURIKI TAKEO, OSAKI TSUTOMU, SAKAKIBARA NISAKU
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:	NEW MATERIAL:The 1,3,6,7-tetrahydro-7-oxo-imidazo[4,5-C][1,2,6]thiadiazine 2-oxide derivative of formula I [R1, R2 and R4 are (substituted)alkyl, aryl or aralkyl; R3 is H, halogen, (substituted)alkyl, (substituted)aryl or (substituted) aralkyl]. EXAMPLE:1-Hexyl-1,3,6,7-tetrahydro-3,6-dimethyl-7-oxo-imidazo[4,5-C][1 ,2,6]thia diazine 2-oxide. USE:A hypotensor and vasodilator. PREPARATION:An imidazole derivative of formula II is made to react with a thionyl halide and, as necessary, the obtained compound is made to react with a halogenating agent.