PHOSPHATE OF RESORUFINE, ITS PRODUCTION AND PHOSPHATASE DETECTING DIAGNOSTIC AGENT CONTAINING THE SAME

The present invention provides phosphates of resorufin derivatives of the general formulae: (Ia) (Ib) wherein R2 and R5, which can be the same or different, are hydrogen or halogen atoms or lower alkyl radicals, R1, R3, R4 and R6, which can be the same or different, are hydrogen or halogen atoms, cy...

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Bibliographische Detailangaben
Hauptverfasser:	KURAUSU MIYUURETSUGAA, HERUBERUTO FUON DERU ERUTSU
Format:	Patent
Sprache:	eng
Schlagworte:	ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention provides phosphates of resorufin derivatives of the general formulae: (Ia) (Ib) wherein R2 and R5, which can be the same or different, are hydrogen or halogen atoms or lower alkyl radicals, R1, R3, R4 and R6, which can be the same or different, are hydrogen or halogen atoms, cyano or carboxy groups or lower alkyl, lower alkoxy, lower alkoxycarbonyl, carboxy lower alkyl or lower alkoxycarbonyl lower alkyl radicals or carboxamide groups which are optionally mono- or disubstituted or radicals of the general formula -COO-(CH2CH2O)n-R7, R7 being a hydrogen atom or a lower alkyl radical and n being a whole number of from 1 to 4, and wherein R6 can additionally also be a sulphonyl or nitro group, Y is a nitrogen atom or an N->O group and M and M', which can be the same or different, are hydrogen atoms or alkali metal, alkaline earth metal or ammonium ions. The present invention also provides processes for the preparation of these compounds and diagnostic agents containing them for the detection of phosphatases.