STABLE PROSTAGLANDIN COMPOSITION

PURPOSE:To obtain a stable prostaglandin composition useful as an odynopoeia agent, vasodilator, suppressing agent for secretion of acid in the stomach, etc., having hormone-like action, by blending physiologically active prostaglandin with vinyl acetate resin. CONSTITUTION:Prostaglandin is blended...

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Bibliographische Detailangaben
Hauptverfasser:	YAMADA AKIYA, TSUZUKI NORIKO, KONISHI RYOSHI
Format:	Patent
Sprache:	eng
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	PURPOSE:To obtain a stable prostaglandin composition useful as an odynopoeia agent, vasodilator, suppressing agent for secretion of acid in the stomach, etc., having hormone-like action, by blending physiologically active prostaglandin with vinyl acetate resin. CONSTITUTION:Prostaglandin is blended with 10-10,000 times as much as vinyl acetate resin. The prostaglandin and the vinyl acetate resin are dissolved in an organic solvent such as methanol, acetone, ethyl acetate, etc., or a mixed solvent thereof and then subjected to vacuum drying or through-flow drying to give the aimed substance. The substance can be blended with a proper plasticizer into sheet or mixed with a proper excipient into tablets or capsules. Vinyl acetate resin as a food additive suppresses decomposition of prostaglandin to provide a prostaglandin composition having improved shelf stability.