JPS6354714B

JPS6354714B

New imidazolinylamino-pyrimidine derivs. of formula (I) and their salts are new. In (I) R1-3 are H, halogen or 1-4C alkyl or alkoxy; and R4 is H or an aliphatic or aromatic acyl gp. (I) have hypotensive activity. They induce a long-lasting lowering of blood pressure when administered to spontaneousl...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: BORUFUGANKU FURETSUKU, BEN ARUMAA, EERITSUHI KOONEN, BORUFUGANGU SUTENTSUERU
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:New imidazolinylamino-pyrimidine derivs. of formula (I) and their salts are new. In (I) R1-3 are H, halogen or 1-4C alkyl or alkoxy; and R4 is H or an aliphatic or aromatic acyl gp. (I) have hypotensive activity. They induce a long-lasting lowering of blood pressure when administered to spontaneously or really hypertensive rats in a dosage of 1-30 mg/kg p.o. Dosage for humans is ca. 1-10 mg/day.