JPS634833B

PCT No. PCT/JP81/00320 Sec. 371 Date Jul. 13, 1982 Sec. 102(e) Date Jul. 13, 1982 PCT Filed Nov. 6, 1981 PCT Pub. No. WO82/01707 PCT Pub. Date May 27, 1982.New antibiotic 5057B and process for its preparation. Antibiotic 5057B itself is an acidic material, and its sodium salt has the following physi...

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Hauptverfasser:	MIZUNO TAKU, KUSAKABE YOKO
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOUNDS OF UNKNOWN CONSTITUTION ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES USING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Zusammenfassung:	PCT No. PCT/JP81/00320 Sec. 371 Date Jul. 13, 1982 Sec. 102(e) Date Jul. 13, 1982 PCT Filed Nov. 6, 1981 PCT Pub. No. WO82/01707 PCT Pub. Date May 27, 1982.New antibiotic 5057B and process for its preparation. Antibiotic 5057B itself is an acidic material, and its sodium salt has the following physical and chemical properties: (1) Colorless needles (2) Melting point: 143 DEG -145 DEG C. (3) Elementary analysis (Found %): C, 59.96; H, 9.03; O, 27.60; Na, 3.41 (4) Specific rotation: [ alpha ]D25=+5.5 DEG (C 1, CHCl3) (5) Maximum absorption in ultraviolet absorption spectrum: lambda maxMeOH(E1 cm1%) 290 nm (0.88) (6) Characteristic absorption (cm-1) in infrared absorption spectrum (taken with the potassium bromide tablet: 3480, 3000, 2970, 2812, 1719, 1645, 1595, 1465, 1385, 1160, 1100, 1035, 980 (7) Solubility: soluble in methanol, ethanol, ethyl acetate, chloroform, ether, acetone, and benzene and so forth; insoluble in water (8) Color reaction: positive in the 2,4-dinitrophenylhydrazine reaction; negative in the ninhydrin reaction and the vanilline-sulfuric acid reaction; colors with I2 gas. The antibiotic is prepared by culturing Streptomyces bacteria, and collecting the antibiotic from the culture product.