SUSTAINED RELEASE SOLID AGENT
PURPOSE:To obtain a sustained release solid agent of stomach retention type, containing calcium silicate and hydroxypropylmethyl cellulose. CONSTITUTION:Calcium silicate is blended with hydroxypropylmethyl cellulose and, if necessary, a drug and an additive and pharmaceutically manufactured by a con...
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Zusammenfassung: | PURPOSE:To obtain a sustained release solid agent of stomach retention type, containing calcium silicate and hydroxypropylmethyl cellulose. CONSTITUTION:Calcium silicate is blended with hydroxypropylmethyl cellulose and, if necessary, a drug and an additive and pharmaceutically manufactured by a conventional procedure to give the aimed substance. The amounts of the solid agent blended is 10-80wt.% based on sum of the solid agent of calcium silicate and 20-80wt.% hydroxypropylmethyl cellulose and in the case of the solid agent containing the drug, the amount of the drug blended is =1 apparent density. The solid agent of this invention is a sustained release part and can be further combined with an immediate release part to give a solid agent. |
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