SOLID AGENT CONTAINING LOW-MELTING SUBSTANCE
PURPOSE:To obtain a solid agent having sufficient hardness causing neither sticking nor capping, by blending a low-melting substance with a specific amount of calcium silicate. CONSTITUTION:A low-melting substance having =30wt.% calcium silicate as an absorbent and, if necessary, a drug, silicic anh...
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Zusammenfassung: | PURPOSE:To obtain a solid agent having sufficient hardness causing neither sticking nor capping, by blending a low-melting substance with a specific amount of calcium silicate. CONSTITUTION:A low-melting substance having =30wt.% calcium silicate as an absorbent and, if necessary, a drug, silicic anhydride or other additives and pharmaceutically manufactured by a conventional procedure to give the aimed substance. A vitamin E-related substance is used as the low-melting substance and d-alpha-tocopherol and vitamin A palmitate may be cited. The calcium silicate has 0.08-0.12 apparent specific gravity and large bulk and liquid absorption amount and specific calcium silicate of jairolite type (trade name furolite R) is preferable. |
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