PRODUCTION OF MENAQUINONE-4 BY FERMENTATION

PURPOSE:To produce menaquinone-4 participating in the coagulation of blood and control of calcium in living body, in high efficiency, by culturing a menaquinone-4-producing microorganism in a medium containing lactose as a carbon source. CONSTITUTION:Corynebacterium liquefaciens ATCC 14929, etc., ar...

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Hauptverfasser: ARAI TAKEMITSU, TOMOHIRO SUSUMU, ENDO SHIZUKO
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creator ARAI TAKEMITSU
TOMOHIRO SUSUMU
ENDO SHIZUKO
description PURPOSE:To produce menaquinone-4 participating in the coagulation of blood and control of calcium in living body, in high efficiency, by culturing a menaquinone-4-producing microorganism in a medium containing lactose as a carbon source. CONSTITUTION:Corynebacterium liquefaciens ATCC 14929, etc., are cultured in a medium containing 5-200g/l, preferably 20-180g/l of glucose as a carbon source in addition to nitrogen source, inorganic salts, minor element, etc., at 20-40 deg.C, preferably 25-35 deg.C and pH 5-9, preferably about 7 for 3-7 days under aerobic condition and the objective menaquinone-4 is separated from the cultured product using a solvent, etc.
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CONSTITUTION:Corynebacterium liquefaciens ATCC 14929, etc., are cultured in a medium containing 5-200g/l, preferably 20-180g/l of glucose as a carbon source in addition to nitrogen source, inorganic salts, minor element, etc., at 20-40 deg.C, preferably 25-35 deg.C and pH 5-9, preferably about 7 for 3-7 days under aerobic condition and the objective menaquinone-4 is separated from the cultured product using a solvent, etc.</description><language>eng</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>1988</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19881006&amp;DB=EPODOC&amp;CC=JP&amp;NR=S63240792A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25563,76418</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19881006&amp;DB=EPODOC&amp;CC=JP&amp;NR=S63240792A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>ARAI TAKEMITSU</creatorcontrib><creatorcontrib>TOMOHIRO SUSUMU</creatorcontrib><creatorcontrib>ENDO SHIZUKO</creatorcontrib><title>PRODUCTION OF MENAQUINONE-4 BY FERMENTATION</title><description>PURPOSE:To produce menaquinone-4 participating in the coagulation of blood and control of calcium in living body, in high efficiency, by culturing a menaquinone-4-producing microorganism in a medium containing lactose as a carbon source. 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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
title PRODUCTION OF MENAQUINONE-4 BY FERMENTATION
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