BENZOIMIDAZOLE-2-ONE DERIVATIVES, SALTS, MANUFACTURE AND INTERMEDIATES, USE AS DRUG AND COMPOSITION

Novel benzimidazol-2-ones of the formula I wherein R is selected from the group consisting of hydrogen, alkyl of 1 to 5 carbon atoms, cycloalkylalkyl of 4 to 7 carbon atoms, alkenyl and alkynyl of 3 to 5 carbon atoms with the multiple bond not between the carbons alpha - and beta - to the nitrogen a...

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Hauptverfasser: KONSUTANTAN AGUURIDA, JIRU AMON, RIYUSHIAN NEDERETSUKU, PATORITSUKU FUOOBOO
Format: Patent
Sprache:eng
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Zusammenfassung:Novel benzimidazol-2-ones of the formula I wherein R is selected from the group consisting of hydrogen, alkyl of 1 to 5 carbon atoms, cycloalkylalkyl of 4 to 7 carbon atoms, alkenyl and alkynyl of 3 to 5 carbon atoms with the multiple bond not between the carbons alpha - and beta - to the nitrogen and aralkyl of 7 to 12 carbon atoms optionally substituted with at least one member of the group consisting of halogen and alkyl and alkoxy of 1 to 5 carbon atoms and R1 is selected from the group consisting of hydrogen, -OH, alkoxy of 1 to 5 carbon atoms, phenoxy and phenylalkoxy of 7 to 9 carbon atoms and their non-toxic, pharmaceutically acceptable acid addition salts having dopaminergic, antiulcerous, and antihypertensive and vasodilatatory activity.