NOVEL PYRROLOBENZIMIDAZOLE, ITS PRODUCTION AND CARDIAC- AND CIRCULATORY SYSTEM DISEASE DRUG CONTAINING THE SAME

Pyrrolobenzimidazoles of the formula: are useful for treatment of heart and circulatory diseases. R1 is substituted phenyl; or optionally substituted naphthyl or a five- or six-membered heterocyclic group which can be condensed with a phenyl ring to form a bicyclic radical. R2 is hydrogen, alkyl, al...

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Hauptverfasser: KURAUSU SHIYUTORAIN, BUARUTAA GUNAARU FURIIBE, ARUFUREETO MERUTENSU, ERUBUIN BEEMU
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creator KURAUSU SHIYUTORAIN
BUARUTAA GUNAARU FURIIBE
ARUFUREETO MERUTENSU
ERUBUIN BEEMU
description Pyrrolobenzimidazoles of the formula: are useful for treatment of heart and circulatory diseases. R1 is substituted phenyl; or optionally substituted naphthyl or a five- or six-membered heterocyclic group which can be condensed with a phenyl ring to form a bicyclic radical. R2 is hydrogen, alkyl, alkenyl or cycloalkenyl; R3 is alkyl, alkenyl or hydroxyalkyl or with R2 together forms cycloakylene; or R2 and R3 together form alkylidene or cycloalkylidene. R4 is hydrogen or lower alkanoyl. X is a valency bond, alkylene, vinylene, imino or carbonylamino. T stands for two hydrogen atoms. When X is a valency bond, R1 can also be hydrogen, hydrocarbyl which may also contain oxygen, amino, sulfur, carbonyl and sulfonyl groups. When X is imino or carbonylamino or when R1 is a bicyclic radical, T can also be oxygen. The compounds also include the tautomers and physiologically acceptable salts with inorganic and organic acids.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title NOVEL PYRROLOBENZIMIDAZOLE, ITS PRODUCTION AND CARDIAC- AND CIRCULATORY SYSTEM DISEASE DRUG CONTAINING THE SAME
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