ORGANOGERMANIUM COMPOUND AND ANALGESIC COMPRISING SAME AS MAIN AGENT

ORGANOGERMANIUM COMPOUND AND ANALGESIC COMPRISING SAME AS MAIN AGENT

NEW MATERIAL:A compound shown by the formula I [R1 and R are H, lower alkyl or (substituted) phenyl; R3 is H or lower alkyl; R4 is lower alkyl]. EXAMPLE:A compound shown by the formula II. USE:An analgesic. PREPARATION:For example, a corresponding trichlorgermanium compound shown by the formula III...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: KAKIMOTO NORIHIRO, HASATO TADAHIKO
Format: Patent
Sprache:eng
Schlagworte:
ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:NEW MATERIAL:A compound shown by the formula I [R1 and R are H, lower alkyl or (substituted) phenyl; R3 is H or lower alkyl; R4 is lower alkyl]. EXAMPLE:A compound shown by the formula II. USE:An analgesic. PREPARATION:For example, a corresponding trichlorgermanium compound shown by the formula III is treated with a dried hydrogen sulfide gas in the presence of a base such as pyridine, etc., in an organic solvent such as benzene, etc., to give a compound shown by the formula I. In the reaction, at the stage of the H2S gas treatment, a trimercapto derivative shown by the formula IV is formed and it may not be isolated. But, when it is isolated, a reaction of removal of hydrogen sulfide occurs between the molecules, to preferably form a structure shown by the formula I.