MEMBRANE ANCHOR/ACTIVE COMPOUND CONJUGATE AND MANUFACTURE

Conjugates are described in which the active ingredient is covalently bonded to the anchoring membrane, which is a compound of the formulae in which A can be: sulphur, oxygen, disulphide (-S-S-), methylene (-CH2-) or -NH-; n = 0 to 5; m = 1 or 2; C* = an asymmetric carbon atom of R or S configuratio...

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Bibliographische Detailangaben
Hauptverfasser: GIYUNTAA YUNGU, IERUKU METSUGAA, KAARU HAINTSU BUIISUMIYURAA, HANSU IERUKU BIYUURINGU, BUORUFUGANGU BESURAA, GEERUHARUTO BETSUKAA
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Sprache:eng
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Zusammenfassung:Conjugates are described in which the active ingredient is covalently bonded to the anchoring membrane, which is a compound of the formulae in which A can be: sulphur, oxygen, disulphide (-S-S-), methylene (-CH2-) or -NH-; n = 0 to 5; m = 1 or 2; C* = an asymmetric carbon atom of R or S configuration, R, R' and R'' are identical or different and are an alkyl, alkenyl or alkynyl group having 7 to 25 carbon atoms or are hydrogen which can optionally be substituted by hydroxyl, amino, oxo, acyl, alkyl or cycloalkyl groups and R1 and R2 are identical or different and are defined as R, R' or R'' or can be -OR, -OCOR, -COOR, -NHCOR or -CONHR and X is an active ingredient or a spacer active ingredient group. The anchoring membrane active ingredient conjugates increase antibody formation.