NOVEL ISOQUINOLINE DERIVATIVE

NEW MATERIAL:A compound expressed by formula I or II (X is alkyl, halogen or nitro; Y is alkyl, halogen, nitro, amino, OH or carboxy; R is alkyl; m and n are 0-2). USE:An agricultural or horticultural germicide or intermediate therefor. PREPARATION:The nuclear nitrogen atom of isoquinoline is alkyla...

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Bibliographische Detailangaben
Hauptverfasser:	OKAZAKI HIROSHI, FURUKAWA NOBUYUKI, YOSHIKAWA TAKASHI, WATANABE SHIYUNNOSUKE, SOEDA MAHITO
Format:	Patent
Sprache:	eng
Schlagworte:	AGRICULTURE ANIMAL HUSBANDRY BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES CHEMISTRY FISHING FORESTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HUNTING METALLURGY ORGANIC CHEMISTRY PEST REPELLANTS OR ATTRACTANTS PLANT GROWTH REGULATORS PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF TRAPPING
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Beschreibung
Zusammenfassung:	NEW MATERIAL:A compound expressed by formula I or II (X is alkyl, halogen or nitro; Y is alkyl, halogen, nitro, amino, OH or carboxy; R is alkyl; m and n are 0-2). USE:An agricultural or horticultural germicide or intermediate therefor. PREPARATION:The nuclear nitrogen atom of isoquinoline is alkylated with an alkylating agent, e.g. alkyl halide, etc., to give an N-alkylisoquinolinium salt, which is then reacted with indole in the presence of an alkali to provide a compound expressed by formula II. The resultant compound expressed by formula II is then hydrogenated with sodium borohydride, catalytically hydrogenated in the presence of a platinum catalyst, etc., to afford the aimed compound expressed by formula I.