HUMAN CALCITONIN PRECURSOR PEPTIDE AND PRODUCTION THEREOF
NEW MATERIAL:A compound expressed by formula I (P is peptide residue having amino acid sequence of human calcitonin). USE:A remedy for hypercalcemia, Behcet's disease, etc. PREPARATION:For example, a microorganism, e.g. Escherichia coli, etc. is transformed with a plasmid containing a DNA conta...
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| creator | KIMIZUKA FUSAO OBAYASHI AKIRA KOMINE YURIKO KONDO AKIHIRO KINOSHITA RITSU ISHINO YOSHIZUMI |
| description | NEW MATERIAL:A compound expressed by formula I (P is peptide residue having amino acid sequence of human calcitonin). USE:A remedy for hypercalcemia, Behcet's disease, etc. PREPARATION:For example, a microorganism, e.g. Escherichia coli, etc. is transformed with a plasmid containing a DNA containing a gene capable of coding a peptide expressed by formula II (n is a positive integer) and then cultivated in a culture medium to produce a fused protein containing the peptide expressed by formula II in the resultant culture. The above-mentioned fused protein is then treated with an enzyme, e.g. trypsin, etc., to afford the aimed human calcitonin precursor peptide expressed by formula I. |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES USING MICROORGANISMS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE |
| title | HUMAN CALCITONIN PRECURSOR PEPTIDE AND PRODUCTION THEREOF |
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