ANTIASTHMATIC AND BRONCHODILATOR

The present invention is concerned with the use of azoniaspironortropanol esters of the general formula: (I) wherein R signifies one of the following radicals: (a) an alkylene radical of the general formula: in which R3 is a hydrogen atom or an alkyl, benzyl, aryl or alkoxy radical and n is a whole number of from 1 to 4, (b) an alkenyl radical of the general formula: in which R4 and R5, which can be the same or different, are hydrogen atoms or alkyl or alkenyl radicals and n is a whole number of from 1 to 4, (c) an azaalkylene radical of the general formula: in which R6 is a hydrogen atom or an alkyl, alkoxycarbonyl or acyl radical and n is a whole number of from 2 to 4, (d) an oxaalkylene radical of the general formula: -(CH2)n-O-(CH2)n- in which n is a whole number of from 2 to 4, (e) an epoxyalkylene radical of the formula: (f) an o-phenylene radical of the general formula: (g) a per-naphthylene radical of the general formula: or (h) a 2,3-quinoxalinene radical of the general formula: in which in formulae (f) to (h), the symbols X and Y, which can be the same or different, are hydrogen atoms or alkyl or alkoxy radicals; and wherein R1 and R2, which can be the same or different, are hydrogen or halogen atoms or alkyl, alkoxy, alkoyl, cyclohexyl, phenyl, alkylphenyl, alkoxyphenyl, halophenyl, thienyl or furyl radicals, the alkyl moieties in the said radicals containing up to 6 carbon atoms and being straight-chained or branched, and A(-) is the anion of a mono- to tribasic mineral acid, as asthma therapeutics or broncholytics.