INDINO(1,7-CD)AZEPINES

INDINO(1,7-CD)AZEPINES

Compounds of structure (I) …… in which Ar is furyl, thienyl, phenyl or phenyl which is substituted with 1 or 2 methoxy, hydroxy, halo or methyl groups; R is hydrogen, C3-6 allyl or C1-4-alkyl; and R and R are, each, hydrogen, C1-4alkoxy, hydroxy, halo or trifluoromethyl, at least one of R and R bein...

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Bibliographische Detailangaben
Hauptverfasser: HAI JIYA OO, JIYOSEFU UEINSUTOTSUKU, KAARU KAIZAA
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Compounds of structure (I) …… in which Ar is furyl, thienyl, phenyl or phenyl which is substituted with 1 or 2 methoxy, hydroxy, halo or methyl groups; R is hydrogen, C3-6 allyl or C1-4-alkyl; and R and R are, each, hydrogen, C1-4alkoxy, hydroxy, halo or trifluoromethyl, at least one of R and R being other than hydrogen, and pharmaceutically acceptable acid addition salts thereof, processes for their preparation, pharmaceutical compositions containing them and their use in therapy as dopamine antagonists.