DOPAMINE-BETA-HYDROXYLASE INHIBITOR

DOPAMINE-BETA-HYDROXYLASE INHIBITOR

Compounds of formula in which: n is 0-5; R is hydrogen or C1-4 alkyl; and X is hydrogen, halo, C1-4 alkyl, CN, NO2 SO2NH2, COOH, CHO, OH, CH2OH, C1-4 alkoxy, CF3, SO2CH3, SO2CF3, or CO2CaH2a+1 where a is 1-5, or any accessible combination thereof of up to 5 substituents; processes for their preparat...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: JIYOSEFU ARAN FUINKERUSUTAIN, KAARU KAIZAA, ROURENSU AIBAN KURUSU
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Compounds of formula in which: n is 0-5; R is hydrogen or C1-4 alkyl; and X is hydrogen, halo, C1-4 alkyl, CN, NO2 SO2NH2, COOH, CHO, OH, CH2OH, C1-4 alkoxy, CF3, SO2CH3, SO2CF3, or CO2CaH2a+1 where a is 1-5, or any accessible combination thereof of up to 5 substituents; processes for their preparation, intermediates useful in their preparation, pharmaceutical compositions containing them and their use in therapy as dopamine- beta -hydroxylase inhibitors.