MANUFACTURE OF SUBSTITUTED INDOLINE

MANUFACTURE OF SUBSTITUTED INDOLINE

Indoline derivs. of formula (I) are prepd. by reducing indole derivs. of formula (II) with Mg in an alcohol-contg. solvent. In the formulas, R1 is H, methyl or lower alkoxy; R2 is H or acetyl; R3 is methoxy, ethoxy, amide, N-methylamide; R4 is H or lower alkyl. (I) are useful as intermediates for an...

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Bibliographische Detailangaben
Hauptverfasser: EN KEIKAN, IN JINKEN, BOKU SHIYOUSHIYOKU
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Zusammenfassung:Indoline derivs. of formula (I) are prepd. by reducing indole derivs. of formula (II) with Mg in an alcohol-contg. solvent. In the formulas, R1 is H, methyl or lower alkoxy; R2 is H or acetyl; R3 is methoxy, ethoxy, amide, N-methylamide; R4 is H or lower alkyl. (I) are useful as intermediates for angiotensin-converting enzyme.