NOVEL ARYLOXYPROPANOLAMINE

Disclosed are novel compounds having the formula wherein R1 is a hydrogen or halogen atom, a lower alkyl, lower alkoxy, lower alkoxy lower alkyl, lower alkenyl, lower alkenyl oxy, cyano, hydroxy, trifluoromethyl, nitro, amino, aminocarbonylmethyl, lower monoalkylamino, lower dialkylamino group; R2 i...

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Bibliographische Detailangaben
Hauptverfasser: FURANTSU ETSUSAA, HERUBERUTO KOTSUPE, BUORUFUGANGU ABERE, BUORUFUGANGU HEFUKE, BUORUFURAMU GAIDA
Format: Patent
Sprache:eng
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Zusammenfassung:Disclosed are novel compounds having the formula wherein R1 is a hydrogen or halogen atom, a lower alkyl, lower alkoxy, lower alkoxy lower alkyl, lower alkenyl, lower alkenyl oxy, cyano, hydroxy, trifluoromethyl, nitro, amino, aminocarbonylmethyl, lower monoalkylamino, lower dialkylamino group; R2 is a hydrogen or halogen atom, cyano, lower alkyl or lower alkoxy or acylamino group; R3 is a hydrogen or halogen atom, a lower alkyl or lower alkoxy group, while R2 and R3 together can also be a butadienyl or methylene dioxy group; R4 is a hydrogen atom or a lower alkyl group; R5 is a chlorine atom or a trifluoromethyl group; X is an alkylene group; and the non-toxic, pharmaceutically acceptable acid addition salts thereof. The compounds are suitable for treatment and prophylaxis of hypertension.