BASE FOR DRUG PREPARATION

PURPOSE:To obtain a base for solid drug reparation, capable of freely controlling the release of the drug and having both rapid-releasing and slow-releasing activity to a drug, by dissolving a pH-dependent enteric polymer under specific condition in a polyalkylene glycol which is solid at room tempe...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: KIMURA KEIICHI, KATOU YUKITAKA, RIKU JIYUICHI
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:PURPOSE:To obtain a base for solid drug reparation, capable of freely controlling the release of the drug and having both rapid-releasing and slow-releasing activity to a drug, by dissolving a pH-dependent enteric polymer under specific condition in a polyalkylene glycol which is solid at room temperature. CONSTITUTION:The objective base can be produced by dissolving (A) a pH- dependent enteric polymer (e.g. cellulose acetate phthalate) having the following characteristics in (B) a polyalkylene glycol (e.g. polyethylene glycol) which is solid at room temperature, preferably at