PHENACYL DERIVATIVE
NEW MATERIAL:A compound shown by the formula I (R1 and R2 are H, halogen, lower alkyl, hydroxy, or lower alkoxy) or its acid addition salt. EXAMPLE:2-[N-(2,6-Dichorophenyl)-N-phenacylamino]-2-imidazoline. USE:A preventive and remedy for cardiac incompetence or diseases of coronary artery, or arrhyth...
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| creator | UEDA YOICHIRO AWAYA AKIRA SATO KAZUO KAMIYA JOJI KITANO TAKASHI SHIRAI SHUZO NAKANO TAKUO |
| description | NEW MATERIAL:A compound shown by the formula I (R1 and R2 are H, halogen, lower alkyl, hydroxy, or lower alkoxy) or its acid addition salt. EXAMPLE:2-[N-(2,6-Dichorophenyl)-N-phenacylamino]-2-imidazoline. USE:A preventive and remedy for cardiac incompetence or diseases of coronary artery, or arrhythmia of heart. A hypotensive. An anti-inflammatory drug. An analgesic. PREPARATION:A 2-(2,6-dichloroanilino)-2-imidazoline shown by the formula II is reacted with a substituted phenacyl derivative shown by the formula III (X is halogen, paratoluenesulfonyloxy, etc.) to give a compound shown by the formula I. |
| format | Patent |
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PREPARATION:A 2-(2,6-dichloroanilino)-2-imidazoline shown by the formula II is reacted with a substituted phenacyl derivative shown by the formula III (X is halogen, paratoluenesulfonyloxy, etc.) to give a compound shown by the formula I.</description><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>1986</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19860718&DB=EPODOC&CC=JP&NR=S61158968A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19860718&DB=EPODOC&CC=JP&NR=S61158968A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>UEDA YOICHIRO</creatorcontrib><creatorcontrib>AWAYA AKIRA</creatorcontrib><creatorcontrib>SATO KAZUO</creatorcontrib><creatorcontrib>KAMIYA JOJI</creatorcontrib><creatorcontrib>KITANO TAKASHI</creatorcontrib><creatorcontrib>SHIRAI SHUZO</creatorcontrib><creatorcontrib>NAKANO TAKUO</creatorcontrib><title>PHENACYL DERIVATIVE</title><description>NEW MATERIAL:A compound shown by the formula I (R1 and R2 are H, halogen, lower alkyl, hydroxy, or lower alkoxy) or its acid addition salt. 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EXAMPLE:2-[N-(2,6-Dichorophenyl)-N-phenacylamino]-2-imidazoline. USE:A preventive and remedy for cardiac incompetence or diseases of coronary artery, or arrhythmia of heart. A hypotensive. An anti-inflammatory drug. An analgesic. PREPARATION:A 2-(2,6-dichloroanilino)-2-imidazoline shown by the formula II is reacted with a substituted phenacyl derivative shown by the formula III (X is halogen, paratoluenesulfonyloxy, etc.) to give a compound shown by the formula I.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | PHENACYL DERIVATIVE |
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