TOCOPHEROL DERIVATIVE

NEW MATERIAL:A compound shown by the formula (R1 is glucose, galactose, cellobiose residue or acetylated derivative residue of it; R2 and R3 are H, or CH3). EXAMPLE:Dl-alpha-Tocopherylglucoside. USE:An antisterility vitamin, or an antioxidant. PREPARATION:Tocopherol is reacted with peracetylated sac...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	MASAMOTO KOUZOU, MIYATAKA SUKIYOSHI, SATOU TOSHIO
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY DERIVATIVES THEREOF HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SUGARS
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	NEW MATERIAL:A compound shown by the formula (R1 is glucose, galactose, cellobiose residue or acetylated derivative residue of it; R2 and R3 are H, or CH3). EXAMPLE:Dl-alpha-Tocopherylglucoside. USE:An antisterility vitamin, or an antioxidant. PREPARATION:Tocopherol is reacted with peracetylated saccharide (e.g., beta-D- glucopyranose pentaacetate, etc.) in a solvent (e.g., ethylene glycol diacetate, etc.) in the presence of p-toluenesulfonic acid as a catalyst at 80-100 deg.C for 3-7hr, to give a compound where R1 of the formula is acetylated saccharide residue. This compound is heated under reflux in anhydrous methanol in the presence of NaOCH3, treated with an ion exchange resin, deacetylated, to give a compound such as the example compound, etc. having the corresponding saccharide residue.