ACYLATED 1,2,4-TRIAZOLE DERIVATIVE AND MANUFACTURE

The invention relates to acylated 1,2,4-triazole derivatives of general formula I wherein R1 represents an unsubstituted phenyl group or a phenyl group substituted by one or more halogen atoms, lower alkyl, alkoxy, acyloxy, hydroxy, amino, azido, nitro, trifluoromethyl, lower alkylthio, alkylsulfiny...

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Bibliographische Detailangaben
Hauptverfasser: RAYOSU TORUDEI, RASURO PONGO, TAMASU SOMORAI, TEIBORU RANGU, ISUTOBAN HORUBATO, YOTSUEFU REITERU, GERA SHIRAGI
Format: Patent
Sprache:eng
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Zusammenfassung:The invention relates to acylated 1,2,4-triazole derivatives of general formula I wherein R1 represents an unsubstituted phenyl group or a phenyl group substituted by one or more halogen atoms, lower alkyl, alkoxy, acyloxy, hydroxy, amino, azido, nitro, trifluoromethyl, lower alkylthio, alkylsulfinyl, or alkylsulfonyl group, and R2 stands for a C1-6 alkyl group or a phenyl lower alkyl group which is either unsubstituted or substituted in the aromatic nucleus by a halogen atom or a nitro group, and their pharmaceutically acceptable salts, and a process for preparing them. The new compounds according to the invention exhibit valuable antiviral activity.