SELENIUM-CONTAINING COMPOUND AND DRUG CONTAINING IT AS ACTIVE INGREDIENT
NEW MATERIAL:A selenium-containing compound shown by the formula I or formula II(A is group shown by the formula III, or formula IV; R and R2 are aryl, or alkyl) or its salt. EXAMPLE:4-Methyl-3-phenylcarbamoyl-1,2,5-selenodiazole. USE:A low toxic carcinostatic agent having improved action on Ehrlich...
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creator | UEDA YASUMASA ITOU HITOSHI SAKAKIBARA NISAKU HIDAKA HIROYOSHI |
description | NEW MATERIAL:A selenium-containing compound shown by the formula I or formula II(A is group shown by the formula III, or formula IV; R and R2 are aryl, or alkyl) or its salt. EXAMPLE:4-Methyl-3-phenylcarbamoyl-1,2,5-selenodiazole. USE:A low toxic carcinostatic agent having improved action on Ehrlich ascites carcinoma. PROCESS:A compound shown by the formula V is reacted with selenium dioxide preferably in the presence of a solvent such as dioxane, etc. to give a compound shown by the formula I or formula II. The reaction temperature is preferably 50 deg.C- the boiling point of the reaction mixture, and the reaction finishes usually about an hour. |
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EXAMPLE:4-Methyl-3-phenylcarbamoyl-1,2,5-selenodiazole. USE:A low toxic carcinostatic agent having improved action on Ehrlich ascites carcinoma. PROCESS:A compound shown by the formula V is reacted with selenium dioxide preferably in the presence of a solvent such as dioxane, etc. to give a compound shown by the formula I or formula II. 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EXAMPLE:4-Methyl-3-phenylcarbamoyl-1,2,5-selenodiazole. USE:A low toxic carcinostatic agent having improved action on Ehrlich ascites carcinoma. PROCESS:A compound shown by the formula V is reacted with selenium dioxide preferably in the presence of a solvent such as dioxane, etc. to give a compound shown by the formula I or formula II. The reaction temperature is preferably 50 deg.C- the boiling point of the reaction mixture, and the reaction finishes usually about an hour.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1984</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZPAIdvVx9fMM9dV19vcLcfT08_RzV3D29w3wD_VzUXAEYpegUJAIXNIzRMExWMHROcQzzFUBKBDk6uLp6hfCw8CalphTnMoLpbkZFNxcQ5w9dFML8uNTiwsSk1PzUkvivQKCTS2NDIzMTRyNiVACAL1jLMI</recordid><startdate>19840201</startdate><enddate>19840201</enddate><creator>UEDA YASUMASA</creator><creator>ITOU HITOSHI</creator><creator>SAKAKIBARA NISAKU</creator><creator>HIDAKA HIROYOSHI</creator><scope>EVB</scope></search><sort><creationdate>19840201</creationdate><title>SELENIUM-CONTAINING COMPOUND AND DRUG CONTAINING IT AS ACTIVE INGREDIENT</title><author>UEDA YASUMASA ; ITOU HITOSHI ; SAKAKIBARA NISAKU ; HIDAKA HIROYOSHI</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_JPS5920274A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>1984</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>UEDA YASUMASA</creatorcontrib><creatorcontrib>ITOU HITOSHI</creatorcontrib><creatorcontrib>SAKAKIBARA NISAKU</creatorcontrib><creatorcontrib>HIDAKA HIROYOSHI</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>UEDA YASUMASA</au><au>ITOU HITOSHI</au><au>SAKAKIBARA NISAKU</au><au>HIDAKA HIROYOSHI</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>SELENIUM-CONTAINING COMPOUND AND DRUG CONTAINING IT AS ACTIVE INGREDIENT</title><date>1984-02-01</date><risdate>1984</risdate><abstract>NEW MATERIAL:A selenium-containing compound shown by the formula I or formula II(A is group shown by the formula III, or formula IV; R and R2 are aryl, or alkyl) or its salt. EXAMPLE:4-Methyl-3-phenylcarbamoyl-1,2,5-selenodiazole. USE:A low toxic carcinostatic agent having improved action on Ehrlich ascites carcinoma. PROCESS:A compound shown by the formula V is reacted with selenium dioxide preferably in the presence of a solvent such as dioxane, etc. to give a compound shown by the formula I or formula II. The reaction temperature is preferably 50 deg.C- the boiling point of the reaction mixture, and the reaction finishes usually about an hour.</abstract><oa>free_for_read</oa></addata></record> |
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subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | SELENIUM-CONTAINING COMPOUND AND DRUG CONTAINING IT AS ACTIVE INGREDIENT |
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