CHROMONE-SUBSTITUTED AND THIOCHROMONE-SUBSTITUTED 1, 4-DIHYDROPYRIDINE-LACTONES, MANUFACTURE AND USE

Dihydropyridines of the formula in which R1, R2, R5 and R6 can be hydrogen or various halogen or organic radicals, R4 is an optionally substituted hydrocarbon radical, A is a direct bond, a C1-C20-alkylene chain or a C2-C20-alkenylene chain, which chains are optionally interrupted by O or S X is O o...

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Hauptverfasser: RAINAA GUROOSU, GIYUNTAA TOOMASU, MATEIASU SHIYURAMU, JIIKUFURIITO GORUTOMAN, FURIIDORITSUHI BOTSUSERUTO
Format: Patent
Sprache:eng
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Zusammenfassung:Dihydropyridines of the formula in which R1, R2, R5 and R6 can be hydrogen or various halogen or organic radicals, R4 is an optionally substituted hydrocarbon radical, A is a direct bond, a C1-C20-alkylene chain or a C2-C20-alkenylene chain, which chains are optionally interrupted by O or S X is O or S, and Y is a direct bond, O, S, -NH-or-N-alkyl with 1 to 8 C atoms or a pharmaceutically acceptable salt, are useful as cardiotonic agents for improving heart contractility, antihypotonic agents, for lowering the blood sugar level, for detumescing mucous membranes and for influencing the salt and/or liquid balance.