PREPARATION OF ENTERIC DRUG

PURPOSE:To prepare the titled drug soluble, dispersible and disintegrable rapidly at a specific pH, by coating a drug with a carboxymethylethylcellulose having a specific degree of neutralization. CONSTITUTION:The disintegrability of carboxymethylethylcellolose (CMEC) at 6.0 pH can be remarkably imp...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: OOTSUKA YUUJI, KURIHARA KOUZOU, FUKAZAWA TOSHIO
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:PURPOSE:To prepare the titled drug soluble, dispersible and disintegrable rapidly at a specific pH, by coating a drug with a carboxymethylethylcellulose having a specific degree of neutralization. CONSTITUTION:The disintegrability of carboxymethylethylcellolose (CMEC) at 6.0 pH can be remarkably improved without lowering the disintegration resistance at