CYCLIC PEPTIDE HAVING SOMATOSTATIN ACTIVITY

CYCLIC PEPTIDE HAVING SOMATOSTATIN ACTIVITY

The invention relates to cyclic hexapeptides of the general formula III in which X represents the radical of an L-aminoacid of the general formula IIIa (IIIa) in which A and B are identical or different and denote alkyl having 1 to 3 carbon atoms, or A and B together represent a saturated, unsaturat...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: BUORUFUGANGU KEENIHI, FUORUKAA TEETSU, RORUFU GAIGERU, AKUSERU FURIIDORIHI, YURUGEN KURUTO ZANDOU
Format: Patent
Sprache:eng
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The invention relates to cyclic hexapeptides of the general formula III in which X represents the radical of an L-aminoacid of the general formula IIIa (IIIa) in which A and B are identical or different and denote alkyl having 1 to 3 carbon atoms, or A and B together represent a saturated, unsaturated or aromatic monocyclic or bicyclic structure having 3 to 6 carbon atoms, n denotes 0 or 1, and Y represents an aliphatic or aromatic L-aminoacid the side chain of which can be hydroxylated, and their salts with physiologically tolerated acids, and to a process for their preparation and their use and their intermediates.