PRODUCTION OF NOVEL TYPE OF TABLET CONTAINING IFENPRODYL

PURPOSE:Granules made from lactose and hydroxypropylcellulose, powdery ifenprodyl tartarate and a powdery diluting agent are mixed without a disintegrator and tabletted to produce the titled tablets with a small size that can be taken with ease in high quality and high stability. CONSTITUTION:Granul...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: SAKAI KAZUYA, HAMATAKE TOORU, MIYAMOTO TOMOHISA, NIKAWA HIRAMOTO
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:PURPOSE:Granules made from lactose and hydroxypropylcellulose, powdery ifenprodyl tartarate and a powdery diluting agent are mixed without a disintegrator and tabletted to produce the titled tablets with a small size that can be taken with ease in high quality and high stability. CONSTITUTION:Granules made from lactose and hydroxypropylcellulose, powdery ifenprodyl tartarate and a powdery diluting agent are mixed without a disintegrator to prepare a tabletting composition and the resultant composition is tabletted. As the diluting agent, is used 5-20wt% of crystalline cellulose based on the composition. As a lubricant, is used 0.5-2wt% of magnesium stearate based on the composition. Since a disintegrator is not used, there occurs no deterioration in hardness, weariness and moldability. Troubles can be avoided in deterioration of tablet characteristics and on tabletting operation, because the composition contains a small amount of a binder.