13-HYDROXYMYCINAMICIN DERIVATIVE

NEW MATERIAL:A compound shown by the formulaI(A is a group shown by the formula II when R is H, a group shown by the formula III when R is OH, and a group shown by the formula IV when R is a group constituting 11,14- epoxy group; Q is a group constituting 11,14-epoxy). EXAMPLE:12,13-Deepoxy-13-hydro...

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Hauptverfasser: SAKAKIBARA HIDEO, SATOI SHIYUUZOU, MUTOU NAOKI, OONO MASARU, KINOSHITA KENJI, SHIBUYA YUUZOU, HAYASHI MITSUO, TAKADA MASAKI
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creator SAKAKIBARA HIDEO
SATOI SHIYUUZOU
MUTOU NAOKI
OONO MASARU
KINOSHITA KENJI
SHIBUYA YUUZOU
HAYASHI MITSUO
TAKADA MASAKI
description NEW MATERIAL:A compound shown by the formulaI(A is a group shown by the formula II when R is H, a group shown by the formula III when R is OH, and a group shown by the formula IV when R is a group constituting 11,14- epoxy group; Q is a group constituting 11,14-epoxy). EXAMPLE:12,13-Deepoxy-13-hydroxymycinamicinI. USE:An oral or injection remedy for infectious deseases caused by Gram-positive bacteria or mycoplasm or an animal growth promotor. PROCESS:(A) Mycinamicin(MMN)Ior MMN II is reacted with an electron donor metal (e.g., zinc powder, etc.) and an ammonium salt (e.g., NH4Cl, etc.) in a hydrous polar solvent (e.g., water/tetrahydrofuran, etc.) or (B) a culture of a bacterium (e.g., Streptomyces variabilis TYJ-689, etc.) capable of converting MMNIor MMN II to the desired substance, its mold, or treated materials thereof are reacted with MMNIor MMN II in an aqueous medium in the absence of O2, to give a compound shown by the formulaI.
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EXAMPLE:12,13-Deepoxy-13-hydroxymycinamicinI. USE:An oral or injection remedy for infectious deseases caused by Gram-positive bacteria or mycoplasm or an animal growth promotor. PROCESS:(A) Mycinamicin(MMN)Ior MMN II is reacted with an electron donor metal (e.g., zinc powder, etc.) and an ammonium salt (e.g., NH4Cl, etc.) in a hydrous polar solvent (e.g., water/tetrahydrofuran, etc.) or (B) a culture of a bacterium (e.g., Streptomyces variabilis TYJ-689, etc.) capable of converting MMNIor MMN II to the desired substance, its mold, or treated materials thereof are reacted with MMNIor MMN II in an aqueous medium in the absence of O2, to give a compound shown by the formulaI.</description><language>eng</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; DERIVATIVES THEREOF ; ENZYMOLOGY ; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; MICROBIOLOGY ; MUTATION OR GENETIC ENGINEERING ; NUCLEIC ACIDS ; NUCLEOSIDES ; NUCLEOTIDES ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PROCESSES USING MICROORGANISMS ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; SPIRITS ; SUGARS ; VINEGAR ; WINE</subject><creationdate>1983</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19830401&amp;DB=EPODOC&amp;CC=JP&amp;NR=S5855498A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19830401&amp;DB=EPODOC&amp;CC=JP&amp;NR=S5855498A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>SAKAKIBARA HIDEO</creatorcontrib><creatorcontrib>SATOI SHIYUUZOU</creatorcontrib><creatorcontrib>MUTOU NAOKI</creatorcontrib><creatorcontrib>OONO MASARU</creatorcontrib><creatorcontrib>KINOSHITA KENJI</creatorcontrib><creatorcontrib>SHIBUYA YUUZOU</creatorcontrib><creatorcontrib>HAYASHI MITSUO</creatorcontrib><creatorcontrib>TAKADA MASAKI</creatorcontrib><title>13-HYDROXYMYCINAMICIN DERIVATIVE</title><description>NEW MATERIAL:A compound shown by the formulaI(A is a group shown by the formula II when R is H, a group shown by the formula III when R is OH, and a group shown by the formula IV when R is a group constituting 11,14- epoxy group; Q is a group constituting 11,14-epoxy). EXAMPLE:12,13-Deepoxy-13-hydroxymycinamicinI. USE:An oral or injection remedy for infectious deseases caused by Gram-positive bacteria or mycoplasm or an animal growth promotor. PROCESS:(A) Mycinamicin(MMN)Ior MMN II is reacted with an electron donor metal (e.g., zinc powder, etc.) and an ammonium salt (e.g., NH4Cl, etc.) in a hydrous polar solvent (e.g., water/tetrahydrofuran, etc.) or (B) a culture of a bacterium (e.g., Streptomyces variabilis TYJ-689, etc.) capable of converting MMNIor MMN II to the desired substance, its mold, or treated materials thereof are reacted with MMNIor MMN II in an aqueous medium in the absence of O2, to give a compound shown by the formulaI.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>DERIVATIVES THEREOF</subject><subject>ENZYMOLOGY</subject><subject>FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>NUCLEIC ACIDS</subject><subject>NUCLEOSIDES</subject><subject>NUCLEOTIDES</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PROCESSES USING MICROORGANISMS</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>SPIRITS</subject><subject>SUGARS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1983</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZFAwNNb1iHQJ8o-I9I109vRz9PUEkgourkGeYY4hnmGuPAysaYk5xam8UJqbQcHNNcTZQze1ID8-tbggMTk1L7Uk3isg2NTC1NTE0sLRmAglANFTIiE</recordid><startdate>19830401</startdate><enddate>19830401</enddate><creator>SAKAKIBARA HIDEO</creator><creator>SATOI SHIYUUZOU</creator><creator>MUTOU NAOKI</creator><creator>OONO MASARU</creator><creator>KINOSHITA KENJI</creator><creator>SHIBUYA YUUZOU</creator><creator>HAYASHI MITSUO</creator><creator>TAKADA MASAKI</creator><scope>EVB</scope></search><sort><creationdate>19830401</creationdate><title>13-HYDROXYMYCINAMICIN DERIVATIVE</title><author>SAKAKIBARA HIDEO ; SATOI SHIYUUZOU ; MUTOU NAOKI ; OONO MASARU ; KINOSHITA KENJI ; SHIBUYA YUUZOU ; HAYASHI MITSUO ; TAKADA MASAKI</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_JPS5855498A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>1983</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>DERIVATIVES THEREOF</topic><topic>ENZYMOLOGY</topic><topic>FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>NUCLEIC ACIDS</topic><topic>NUCLEOSIDES</topic><topic>NUCLEOTIDES</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PROCESSES USING MICROORGANISMS</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>SPIRITS</topic><topic>SUGARS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>SAKAKIBARA HIDEO</creatorcontrib><creatorcontrib>SATOI SHIYUUZOU</creatorcontrib><creatorcontrib>MUTOU NAOKI</creatorcontrib><creatorcontrib>OONO MASARU</creatorcontrib><creatorcontrib>KINOSHITA KENJI</creatorcontrib><creatorcontrib>SHIBUYA YUUZOU</creatorcontrib><creatorcontrib>HAYASHI MITSUO</creatorcontrib><creatorcontrib>TAKADA MASAKI</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>SAKAKIBARA HIDEO</au><au>SATOI SHIYUUZOU</au><au>MUTOU NAOKI</au><au>OONO MASARU</au><au>KINOSHITA KENJI</au><au>SHIBUYA YUUZOU</au><au>HAYASHI MITSUO</au><au>TAKADA MASAKI</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>13-HYDROXYMYCINAMICIN DERIVATIVE</title><date>1983-04-01</date><risdate>1983</risdate><abstract>NEW MATERIAL:A compound shown by the formulaI(A is a group shown by the formula II when R is H, a group shown by the formula III when R is OH, and a group shown by the formula IV when R is a group constituting 11,14- epoxy group; Q is a group constituting 11,14-epoxy). EXAMPLE:12,13-Deepoxy-13-hydroxymycinamicinI. USE:An oral or injection remedy for infectious deseases caused by Gram-positive bacteria or mycoplasm or an animal growth promotor. PROCESS:(A) Mycinamicin(MMN)Ior MMN II is reacted with an electron donor metal (e.g., zinc powder, etc.) and an ammonium salt (e.g., NH4Cl, etc.) in a hydrous polar solvent (e.g., water/tetrahydrofuran, etc.) or (B) a culture of a bacterium (e.g., Streptomyces variabilis TYJ-689, etc.) capable of converting MMNIor MMN II to the desired substance, its mold, or treated materials thereof are reacted with MMNIor MMN II in an aqueous medium in the absence of O2, to give a compound shown by the formulaI.</abstract><oa>free_for_read</oa></addata></record>
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
DERIVATIVES THEREOF
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROCESSES USING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
SUGARS
VINEGAR
WINE
title 13-HYDROXYMYCINAMICIN DERIVATIVE
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