PRODUCTION OF SPIRAMYCIN1

PURPOSE:A microorganism in Streptomyces is cultured to produce in high efficiency only spiramycinIwith no production of spiramycin II and III. CONSTITUTION:A microoganism in Streptomyces, which is capable of producing only spiramycinIbut deficient in producing spiramycin II and III, such as Streptom...

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Bibliographische Detailangaben
Hauptverfasser:	KAWAHARA SHIN, HAGIWARA TAKESHIGE, SAKURAI MINORI
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA DERIVATIVES THEREOF ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES USING MICROORGANISMS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS SUGARS VINEGAR WINE
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Beschreibung
Zusammenfassung:	PURPOSE:A microorganism in Streptomyces is cultured to produce in high efficiency only spiramycinIwith no production of spiramycin II and III. CONSTITUTION:A microoganism in Streptomyces, which is capable of producing only spiramycinIbut deficient in producing spiramycin II and III, such as Streptomyces ambofacines CS-93 (NRRL12511) is inoculated in an enriched culture medium and aerobically cultured, preferably at a pH of 6-8 and 24-30 deg.C. Then spiramycinIis collected from the culture mixture.