PREPARATION OF APRAMYCIN AND OXYAPRAMYCIN

PURPOSE:To prepare apramycin and oxyapramycin, by cultivating a microorganism belonging to the genus Saccharopolyspora. CONSTITUTION:A microorganism such as Saccharopolyspora sp. Ac 2580(FERM- P 6239) belonging to the genus Saccharopolyspora, capable of producing apramycin and/or oxyapramycin is ino...

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Bibliographische Detailangaben
Hauptverfasser: SAKAKIBARA HIDEO, SATOI SHIYUUZOU, MUTOU NAOKI, TAKADA MASAKI, AWATA MASASHI
Format: Patent
Sprache:eng
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Zusammenfassung:PURPOSE:To prepare apramycin and oxyapramycin, by cultivating a microorganism belonging to the genus Saccharopolyspora. CONSTITUTION:A microorganism such as Saccharopolyspora sp. Ac 2580(FERM- P 6239) belonging to the genus Saccharopolyspora, capable of producing apramycin and/or oxyapramycin is inoculated into a nutritive medium, cultivated at pH slightly acidic or neutral at 30-45 deg.C under aerobic conditions, apramycin and/or oxyapramycin is collected from the culture solution.